SCHEMBL30557461

SCHEMBL30557461

Cc1cccc(NC(=S)Nc2cccc(C)c2)c1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.77
KMT2A Q03164 5/20 0.77
MAPT P10636 3/20 0.77
CYP1A2 P05177 3/20 0.77
NPSR1 Q6W5P4 2/20 0.77
CYP3A4 P08684 2/20 0.77
CYP2C19 P33261 2/20 0.77
CYP2D6 P10635 1/20 0.77
ALDH1A1 P00352 4/20 0.74
GAA P10253 2/20 0.74
RAB9A P51151 1/20 0.68
HPGD P15428 3/20 0.65
SMN1; SMN2 Q16637 2/20 0.65
ALOX12 P18054 2/20 0.65
HTT P42858 3/20 0.63
POLB P06746 2/20 0.63
HSD17B10 Q99714 1/20 0.62
KDM4E B2RXH2 1/20 0.60
LMNA P02545 2/20 0.59
NPC1 O15118 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9453941 1.00 MEN1 (0.77) MEN1KMT2AMAPTCYP1A2NPSR1
SCHEMBL11674611 0.94 KMT2A (0.75) MEN1KMT2AMAPTCYP1A2NPSR1
SCHEMBL11839367 0.90 KMT2A (0.65) MEN1KMT2AMAPTCYP1A2NPSR1
SCHEMBL16566480 0.89 MEN1 (0.80) MEN1KMT2AMAPTCYP1A2NPSR1
SCHEMBL29488189 0.88 CYP1A2 (0.68) MEN1KMT2AMAPTCYP1A2NPSR1
SCHEMBL27860201 0.88 CYP1A2 (0.68) MEN1KMT2AMAPTCYP1A2NPSR1
SCHEMBL6819398 0.88 MAPT (0.71) MEN1KMT2AMAPTCYP1A2NPSR1
SCHEMBL17084267 0.86 ALDH1A1 (0.60) MEN1KMT2AMAPTCYP1A2NPSR1
SCHEMBL14120200 0.86 MAPT (1.00) MEN1KMT2AMAPTCYP1A2NPSR1
SCHEMBL13754517 0.85 ALOX12 (0.62) MEN1KMT2AMAPTCYP1A2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119707777-A Synthesis method of asymmetric thiourea compound 浙江工业大学 2025-03-28 CN disclosed
CN-112533967-B Oil-in-water droplet type emulsion of active energy ray-curable resin composition and thermosensitive recording material 日本化药株式会社 2023-09-15 CN disclosed