Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 6/20 | 0.37 |
| ▸ | SHBG | P04278 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24272949 | 0.84 | MAPT (0.50) | CNR2TAAR1KIF11SHBGCNR1 | |
| SCHEMBL8354437 | 0.84 | KIF11 (0.48) | CNR2TAAR1KIF11SHBGCNR1 | |
| SCHEMBL29570669 | 0.82 | KIF11 (0.47) | TAAR1MAOBKIF11 | |
| SCHEMBL5147319 | 0.81 | TAAR1 (0.67) | TAAR1KIF11 | |
| SCHEMBL10961852 | 0.80 | TAAR1 (0.65) | CNR2TAAR1MAOBKIF11SHBG | |
| Hydrochloric Acid SCHEMBL8615621 | 0.77 | KIF11 (0.51) | TAAR1MAOBKIF11NPC1MAPT | |
| SCHEMBL475887 | 0.76 | CNR2 (0.44) | CNR2TAAR1KIF11CNR1 | |
| SCHEMBL2813687 | 0.74 | LOXL2 (0.48) | MAPTRAB9A | |
| SCHEMBL23126312 | 0.74 | TAAR1 (0.47) | TAAR1MAOBKIF11 | |
| SCHEMBL24069662 | 0.73 | ESRRG (0.37) | CNR2TAAR1CNR1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4564705-A | POLYAMIDE, POLYUREA AND POLYURETHANE MONOMERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-01-14 | — | — | US | disclosed |
| US-4451642-A | Bis(aminoneopentyl) aromatics and polyamides derived therefrom | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-05-29 | — | — | US | disclosed |