Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 16/20 | 0.42 |
| ▸ | AR | P10275 | 2/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP46A1 | Q9Y6A2 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10919401 | 0.81 | PGR (0.39) | PGRARNR3C1NR3C2 | |
| SCHEMBL10921924 | 0.78 | PDE7A (0.49) | PGRARNR3C1NR3C2 | |
| SCHEMBL10914212 | 0.71 | PGR (0.39) | PGRARNR3C1NR3C2 | |
| SCHEMBL10916485 | 0.71 | PGR (0.52) | PGRARNR3C1NR3C2CYP46A1 | |
| SCHEMBL3380231 | 0.70 | PGR (0.59) | PGRARNR3C1NR3C2 | |
| SCHEMBL10918048 | 0.67 | PGR (0.48) | PGRARNR3C1NR3C2 | |
| SCHEMBL10917967 | 0.67 | CYP3A4 (0.34) | CYP3A4HPGDCRHBPCRHR2HSD17B10 | |
| SCHEMBL10915783 | 0.67 | PGR (0.41) | PGRARNR3C1NR3C2 | |
| SCHEMBL4162611 | 0.66 | PGR (0.73) | PGRARNR3C1NR3C2 | |
| SCHEMBL5116200 | 0.65 | PGR (0.52) | PGRARNR3C1NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0093922-B1 | BENZOXAZIN-2-ONES, THEIR PREPARATION AND THERAPEUTIC AGENTS CONTAINING THESE COMPOUNDS | Dr. Karl Thomae GmbH (DE) | 1986-12-30 | — | — | EP | disclosed |
| US-4518597-A | THROMBOSIS, ARTERIOSCLEROSIS, ANTITUMOR, ANTICOAGULANTS | DR. KARL THOMAE GMBH (DE) | 1985-05-21 | — | — | US | disclosed |
| EP-0093922-A2 | Benzoxazin-2-ones, their preparation and therapeutic agents containing these compounds | Dr. Karl Thomae GmbH (DE) | 1983-11-16 | — | — | EP | disclosed |