Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | F2R | P25116 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13194872 | 0.86 | — | — | |
| SCHEMBL6190098 | 0.81 | ALOX15 (0.56) | ALOX15TSHREPHX1EPHX2KDM1A | |
| SCHEMBL4147752 | 0.81 | ALOX15 (0.53) | ALOX15TSHREPHX1EPHX2KDM1A | |
| Hydrochloric Acid SCHEMBL28859585 | 0.79 | ALOX15 (0.51) | ALOX15TSHREPHX1EPHX2KDM1A | |
| SCHEMBL6189244 | 0.78 | ALOX15 (0.53) | ALOX15TSHREPHX1EPHX2KDM1A | |
| SCHEMBL477247 | 0.78 | ALOX15 (0.58) | ALOX15TSHREPHX1EPHX2KDM1A | |
| SCHEMBL24584907 | 0.77 | ALOX15 (0.55) | ALOX15TSHREPHX1EPHX2KDM1A | |
| SCHEMBL12413705 | 0.77 | ALOX15 (0.51) | ALOX15TSHREPHX1EPHX2KDM1A | |
| Hydrochloric Acid SCHEMBL28212505 | 0.77 | ALOX15 (0.49) | ALOX15TSHREPHX1EPHX2KDM1A | |
| SCHEMBL5773080 | 0.77 | ALOX15 (0.51) | ALOX15TSHREPHX1EPHX2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0061333-B1 | 9-(2-(3-INDOLYL)ETHYL)-1-OXA-4,9-DIAZASPIRO(5.5)UNDECAN-3-ONES | SYNTEX (U.S.A.) INC. (US) | 1986-01-02 | — | — | EP | disclosed |