Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 3/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 2/20 | 0.36 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10942178 | 0.89 | ADRB2 (0.50) | STAT3ADRB2KMT2ACNR1CNR2 | |
| SCHEMBL10919435 | 0.89 | ADRB2 (0.49) | STAT3ADRB2KMT2ACNR1CNR2 | |
| SCHEMBL8038099 | 0.85 | LMNA (0.53) | STAT3ADRB2KMT2ACNR1CNR2 | |
| SCHEMBL6079370 | 0.83 | CNR1 (0.56) | STAT3ADRB2KMT2ACNR1CNR2 | |
| SCHEMBL4270348 | 0.83 | CNR1 (0.56) | STAT3ADRB2KMT2ACNR1CNR2 | |
| SCHEMBL2844967 | 0.78 | ADRB2 (0.68) | STAT3ADRB2KMT2AKDM4EHPGD | |
| SCHEMBL29492858 | 0.78 | ADRB2 (0.68) | STAT3ADRB2KMT2AKDM4EHPGD | |
| SCHEMBL10433195 | 0.77 | STAT3 (0.50) | STAT3ADRB2KMT2ACNR1CNR2 | |
| SCHEMBL9656023 | 0.77 | LMNA (0.53) | STAT3ADRB2KMT2AKDM4EHPGD | |
| SCHEMBL25433200 | 0.76 | STAT3 (0.55) | STAT3ADRB2KMT2AKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0101829-B1 | TRICYCLIC COMPOUNDS, A PROCESS FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS | DAIICHI SEIYAKU CO., LTD. (JP) | 1986-12-30 | — | — | EP | disclosed |
| US-4535161-A | ANTIBIOTIC, BACTERICIDE | DAIICHI SEIYAKU CO., LTD. (JP) | 1985-08-13 | — | — | US | disclosed |
| EP-0101829-A2 | Tricyclic compounds, a process for their production and pharmaceutical compositions containing said compounds | DAIICHI SEIYAKU CO., LTD. (JP) | 1984-03-07 | — | — | EP | disclosed |