Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
| ▸ | CASP3 | P42574 | 8/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | CASP2 | P42575 | 2/20 | 0.56 |
| ▸ | CASP7 | P55210 | 2/20 | 0.56 |
| ▸ | CASP6 | P55212 | 2/20 | 0.56 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.54 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.54 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.54 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.54 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6260497 | 0.80 | CASP3 (0.86) | KDM4EALDH1A1HPGDALOX12CASP3 | |
| SCHEMBL10915866 | 0.80 | KDM4E (0.70) | KDM4EALDH1A1HPGDPOLBCYP1A2 | |
| SCHEMBL5947099 | 0.79 | KDM4E (0.71) | KDM4EALDH1A1HPGDALOX12CASP3 | |
| SCHEMBL11122026 | 0.77 | CA12 (0.73) | KDM4EALDH1A1HPGDPOLBKMT2A | |
| SCHEMBL4462900 | 0.76 | KDM4E (0.66) | KDM4EALDH1A1HPGDALOX12CASP3 | |
| SCHEMBL6261674 | 0.75 | KDM4E (0.76) | KDM4EALDH1A1HPGDALOX12CASP3 | |
| SCHEMBL28854755 | 0.75 | KDM4E (0.75) | KDM4EALDH1A1HPGDALOX12CASP3 | |
| SCHEMBL5838218 | 0.74 | ALDH1A1 (0.69) | KDM4EALDH1A1HPGDALOX12CASP3 | |
| SCHEMBL22033208 | 0.74 | KDM4E (0.92) | KDM4EALDH1A1HPGDALOX12CASP3 | |
| SCHEMBL11586190 | 0.73 | MAPT (0.58) | KDM4EALDH1A1MAPTPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0185618-A2 | Isoindolines, process for their manufacture and their use | CIBA-GEIGY AG (CH) | 1986-06-25 | — | — | EP | disclosed |