Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1057440 | 0.75 | CHRNA7 (0.48) | CHRNA7CHRNA4CHRM2CHRM1CHRM3 | |
| SCHEMBL1286305 | 0.75 | CHRNA7 (0.42) | CHRNA7CHRNA4CHRM2CHRM1CHRM3 | |
| SCHEMBL18268167 | 0.75 | CHRNA7 (0.42) | CHRNA7CHRNA4CHRM2CHRM1CHRM3 | |
| SCHEMBL14027182 | 0.75 | CHRNA7 (0.42) | CHRNA7CHRNA4CHRM2CHRM1CHRM3 | |
| SCHEMBL21573624 | 0.75 | CHRNA7 (0.42) | CHRNA7CHRNA4CHRM2CHRM1CHRM3 | |
| SCHEMBL415807 | 0.75 | CHRNA7 (0.42) | CHRNA7CHRNA4CHRM2CHRM1CHRM3 | |
| SCHEMBL18268169 | 0.75 | CHRNA7 (0.42) | CHRNA7CHRNA4CHRM2CHRM1CHRM3 | |
| SCHEMBL10915261 | 0.75 | CHRNA7 (0.42) | CHRNA7CHRNA4CHRM2CHRM1CHRM3 | |
| SCHEMBL22776221 | 0.75 | CHRNA7 (0.42) | CHRNA7CHRNA4CHRM2CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL10978368 | 0.73 | CHRNA7 (0.41) | CHRNA7CHRNA4CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0102283-B1 | PROCESS FOR THE PREPARATION OF QUINUCLIDINE DERIVATIVES SUBSTITUTED IN POSITION 3 | PHARMUKA LABORATOIRES (FR) | 1986-12-03 | — | — | EP | claimed |
| US-4546185-A | REACTING 3-METHYLENE QUINUCLIDINE WITH AN ALUMINUM HYDRIDE USING SOLVENT AND TRANSITION METAL CATALYST; INSITU REACTING WITH AN ESTERTHEN HALOGENATING AGENT | PHARMUKA LABORATOIRES (FR) | 1985-10-08 | — | — | US | disclosed |