Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18268167 | 1.00 | CHRNA7 (0.42) | CHRNA7CHRM2CHRM1CHRNA4CYP2D6 | |
| SCHEMBL18268169 | 1.00 | CHRNA7 (0.42) | CHRNA7CHRM2CHRM1CHRNA4CYP2D6 | |
| Hydrochloric Acid SCHEMBL10978368 | 0.98 | CHRNA7 (0.41) | CHRNA7CHRM2CHRM1CHRNA4CYP2D6 | |
| SCHEMBL2420280 | 0.88 | — | — | |
| SCHEMBL7318990 | 0.88 | — | — | |
| SCHEMBL7324063 | 0.81 | CHRNA7 (0.39) | CHRNA7CHRM2CHRM1CHRNA4CYP2D6 | |
| SCHEMBL13617347 | 0.81 | CHRNA7 (0.39) | CHRNA7CHRM2CHRM1CHRNA4CYP2D6 | |
| SCHEMBL28703379 | 0.79 | CHRNA7 (0.38) | CHRNA7CHRM2CHRM1CHRNA4CYP2D6 | |
| SCHEMBL7328436 | 0.78 | CHRNA7 (0.37) | CHRNA7CHRM2CHRM1CHRNA4CYP2D6 | |
| Hydrochloric Acid SCHEMBL11442910 | 0.77 | ALDH1A1 (0.40) | CHRM2CHRM1CYP2D6CHRM3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747244-B1 | CO-CATALYSIS OF AUTOCATALYTIC POLYOLS FOR LOW DENSITY POLYURETHANE FOAMS WITH IMPROVED AGING CHARACTERISTICS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-12-28 | — | — | EP | claimed |
| EP-2069417-B1 | POLYURETHANE FOAMS MADE FROM HYDROXYMETHYL-CONTAINING POLYESTER POLYOLS AND TERTIARY AMINE-CONTAINING POLYOLS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-12-12 | — | — | EP | claimed |
| US-20100010110-A1 | POLYURETHANE FOAMS MADE FROM HYDROXYMETHYL-CONTAINING POLYESTER POLYOLS AND TERTIARY AMINE-CONTAINING POLYOLS | DOW GLOBAL TECHNOLOGIES INC (US) | 2010-01-14 | — | — | US | claimed |
| EP-2069417-A1 | POLYURETHANE FOAMS MADE FROM HYDROXYMETHYL-CONTAINING POLYESTER POLYOLS AND TERTIARY AMINE-CONTAINING POLYOLS | Dow Global Technologies Inc. (US) | 2009-06-17 | — | — | EP | claimed |
| WO-2008039657-A1 | POLYURETHANE FOAMS MADE FROM HYDROXYMETHYL-CONTAINING POLYESTER POLYOLS AND TERTIARY AMINE-CONTAINING POLYOLS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2008-04-03 | — | — | WO | claimed |
| US-20070173556-A1 | Co-catalysis of autocatalytic polyols for low denisty polyurethane foams with improved aging characteristics | PRANGE ROBBYN | 2007-07-26 | — | — | US | claimed |
| EP-1747244-A1 | CO-CATALYSIS OF AUTOCATALYTIC POLYOLS FOR LOW DENSITY POLYURETHANE FOAMS WITH IMPROVED AGING CHARACTERISTICS | Dow Gloval Technologies Inc. (US) | 2007-01-31 | — | — | EP | claimed |
| US-20060217516-A1 | Tertiary amine modified polyurethane products made therefrom | CASATI FRANCOIS M | 2006-09-28 | — | — | US | claimed |
| US-20060052570-A1 | Amine-epoxy autocatalytic polymers and polyurethane products made therefrom | GAN JOSEPH | 2006-03-09 | — | — | US | claimed |
| WO-2005111109-A1 | CO-CATALYSIS OF AUTOCATALYTIC POLYOLS FOR LOW DENSITY POLYURETHANE FOAMS WITH IMPROVED AGING CHARACTERISTICS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2005-11-24 | — | — | WO | claimed |
| EP-1470174-A1 | TERTIARY AMINE MODIFIED POLYOLS AND POLYURETHANE PRODUCTS MADE THEREFROM | DOW GLOBAL TECHNOLOGIES INC. (US) | 2004-10-27 | — | — | EP | claimed |
| EP-1442070-A1 | AUTOCATALYTIC POLYOLS WITH GELLING CHARACTERISTICS AND POLYURETHANE PRODUCTS MADE THEREFROM | DOW GLOBAL TECHNOLOGIES INC. (US) | 2004-08-04 | — | — | EP | claimed |
| WO-2004060956-A1 | AMINE-EPOXY AUTOCATALYTIC POLYMERS AND POLYURETHANE PRODUCTS MADE THEREFROM | DOW GLOBAL TECHNOLOGIES INC. (US) | 2004-07-22 | — | — | WO | claimed |
| WO-2003055930-A1 | TERTIARY AMINE MODIFIED POLYOLS AND POLYURETHANE PRODUCTS MADE THEREFROM | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-07-10 | — | — | WO | claimed |
| WO-2003029320-A1 | AUTOCATALYTIC POLYOLS WITH GELLING CHARACTERISTICS AND POLYURETHANE PRODUCTS MADE THEREFROM | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-04-10 | — | — | WO | claimed |
| EP-0747407-B1 | Hydroxymethyl quinuclidine catalyst compositions for making polyurethane foams | AIR PROD & CHEM (US) | 1999-01-13 | — | — | EP | claimed |
| US-5710191-A | Hydroxymethyl quinuclidine catalyst compositions for making polyurethane foams | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1998-01-20 | — | — | US | claimed |
| EP-0747407-A1 | Hydroxymethyl quinuclidine catalyst compositions for making polyurethane foams | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1996-12-11 | — | — | EP | claimed |
| US-4925942-A | Preparation of quinuclidine-3-methanol | RUTGERSWERKE AG (DE) | 1990-05-15 | — | — | US | claimed |
| EP-0102283-B1 | PROCESS FOR THE PREPARATION OF QUINUCLIDINE DERIVATIVES SUBSTITUTED IN POSITION 3 | PHARMUKA LABORATOIRES (FR) | 1986-12-03 | — | — | EP | claimed |