Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10918279 | 0.85 | ALDH1A1 (0.38) | MAPTTSHR | |
| SCHEMBL11245438 | 0.83 | TP53 (0.34) | — | |
| SCHEMBL11240537 | 0.80 | HSD17B10 (0.39) | TSHR | |
| SCHEMBL11235283 | 0.80 | ALDH1A1 (0.39) | MAPTADORA2BADORA1MCL1 | |
| SCHEMBL11253207 | 0.76 | RGS12 (0.30) | TSHR | |
| SCHEMBL11247825 | 0.74 | ALDH1A1 (0.38) | MAPTTSHR | |
| SCHEMBL9622596 | 0.72 | ADORA2B (0.42) | MAPTADORA2BADORA1 | |
| SCHEMBL9622594 | 0.72 | ADORA2B (0.42) | MAPTADORA2BADORA1 | |
| SCHEMBL11236134 | 0.71 | ALDH1A1 (0.43) | MAPTADORA2BTSHR | |
| SCHEMBL11250408 | 0.71 | ALDH1A1 (0.40) | MAPTADORA2BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0099091-B1 | HEXAHYDRODIOXOPYRIMIDINES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1986-10-29 | — | — | EP | disclosed |
| US-4536504-A | ANTITUMOR, ANTIVIRAL, AND ANTIBACTERIAL AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-08-20 | — | — | US | disclosed |
| EP-0099091-A1 | Hexahydrodioxopyrimidines, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1984-01-25 | — | — | EP | disclosed |