Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10919254 | 0.81 | NPC1 (0.47) | NPC1RAB9AKDM4EMAOBL3MBTL1 | |
| SCHEMBL10917982 | 0.79 | SMN1; SMN2 (0.45) | NPC1RAB9AMAOBSMN1; SMN2HSD17B10 | |
| SCHEMBL11149230 | 0.78 | NPC1 (0.43) | NPC1RAB9AKDM4ETDP1MAOB | |
| SCHEMBL8575841 | 0.78 | ALDH1A1 (0.44) | NPC1RAB9AKDM4ETDP1MAOB | |
| SCHEMBL2399420 | 0.77 | NPC1 (0.57) | NPC1RAB9AKDM4ETDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL11148314 | 0.77 | MAOB (0.43) | NPC1RAB9AKDM4ETDP1MAOB | |
| Hydrochloric Acid SCHEMBL10917984 | 0.76 | NPC1 (0.45) | NPC1RAB9AMAOBSMN1; SMN2HSD17B10 | |
| SCHEMBL25062709 | 0.72 | NPC1 (0.45) | NPC1RAB9AKDM4EMAOBSMN1; SMN2 | |
| SCHEMBL5795584 | 0.72 | MAOB (0.48) | NPC1RAB9AKDM4ETDP1MAOB | |
| SCHEMBL11152138 | 0.72 | NPC1 (0.46) | NPC1RAB9AKDM4ETDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048954-A2 | Beta-lactam compounds, process for the preparation thereof and intermediate products for the preparation thereof | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1982-04-07 | — | — | EP | claimed |
| EP-0048954-B1 | BETA-LACTAM COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND INTERMEDIATE PRODUCTS FOR THE PREPARATION THEREOF | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1986-12-30 | — | — | EP | disclosed |
| EP-0048954-A2 | Beta-lactam compounds, process for the preparation thereof and intermediate products for the preparation thereof | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1982-04-07 | — | — | EP | disclosed |