Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10919254 | 0.83 | NPC1 (0.47) | ALDH1A1MAPTNPC1RAB9AKDM4E | |
| SCHEMBL25062709 | 0.81 | NPC1 (0.45) | ALDH1A1MAPTNPC1RAB9AKDM4E | |
| SCHEMBL11149230 | 0.81 | NPC1 (0.43) | ALDH1A1MAPTNPC1RAB9AKDM4E | |
| SCHEMBL2399420 | 0.80 | NPC1 (0.57) | ALDH1A1MAPTNPC1RAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL11148314 | 0.79 | MAOB (0.43) | ALDH1A1MAPTNPC1RAB9AKDM4E | |
| SCHEMBL28262031 | 0.79 | ALDH1A1 (0.42) | ALDH1A1MAPTNPC1RAB9AKDM4E | |
| SCHEMBL10918915 | 0.78 | NPC1 (0.41) | ALDH1A1MAPTNPC1RAB9AKDM4E | |
| SCHEMBL11871660 | 0.78 | NPC1 (0.42) | ALDH1A1MAPTNPC1RAB9AKDM4E | |
| SCHEMBL13656488 | 0.76 | HSD17B10 (0.44) | ALDH1A1MAPTNPC1RAB9AMAOB | |
| SCHEMBL5795584 | 0.74 | MAOB (0.48) | ALDH1A1MAPTNPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5721347-A | Esters and amides of substituted pyrrole acetic acids | CELL PATHWAYS, INC. (US) | 1998-02-24 | — | — | US | disclosed |
| EP-0485157-A2 | Esters and amides of substituted pyrrole acetic acids | FGN, INC. (US) | 1992-05-13 | — | — | EP | disclosed |
| US-3952012-A | MULTISTAGE | MCNEIL LABORATORIES, INCORPORATED (US) | 1976-04-20 | — | — | US | disclosed |