SCHEMBL10918992

SCHEMBL10918992

NC(=O)c1ccc[n+](CO)c1

nearest known ligand 0.69

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.63
NPSR1 Q6W5P4 1/20 0.63
MAPT P10636 3/20 0.56
NNMT P40261 1/20 0.56
HSP90AA1 P07900 7/20 0.55
KMT2A Q03164 2/20 0.54
MEN1 O00255 1/20 0.54
ATM Q13315 1/20 0.49
BACE1 P56817 1/20 0.47
POLB P06746 1/20 0.45
CYP3A4 P08684 1/20 0.45
PARP1 P09874 1/20 0.45
TSHR P16473 1/20 0.45
CYP2C19 P33261 1/20 0.45
RECQL P46063 1/20 0.45
BLM P54132 1/20 0.45
PMP22 Q01453 1/20 0.45
HSD17B10 Q99714 1/20 0.45
TDP1 Q9NUW8 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16674216 0.86 NPSR1 (0.65) L3MBTL1NPSR1MAPTNNMTHSP90AA1
SCHEMBL10915987 0.85 NPSR1 (0.59) L3MBTL1NPSR1MAPTNNMTHSP90AA1
Hydrochloric Acid SCHEMBL3062156 0.84 NPSR1 (0.58) L3MBTL1NPSR1MAPTNNMTHSP90AA1
SCHEMBL677578 0.83 NPSR1 (0.61) L3MBTL1NPSR1MAPTNNMTHSP90AA1
SCHEMBL16673895 0.83 NPSR1 (0.61) L3MBTL1NPSR1MAPTNNMTHSP90AA1
SCHEMBL9811156 0.83 L3MBTL1 (0.61) L3MBTL1NPSR1MAPTNNMTHSP90AA1
SCHEMBL5430523 0.83 MAPT (0.63) L3MBTL1NPSR1MAPTNNMTHSP90AA1
Hydrochloric Acid SCHEMBL3072623 0.81 HSP90AA1 (0.64) L3MBTL1NPSR1MAPTNNMTHSP90AA1
SCHEMBL16673898 0.81 NPSR1 (0.59) L3MBTL1NPSR1MAPTNNMTHSP90AA1
SCHEMBL13934018 0.81 NPSR1 (0.84) L3MBTL1NPSR1MAPTNNMTHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230295211-A1 METHODS OF PRODUCING CRYSTALLINE BETA NICOTINAMIDE RIBOSIDE TRIACETATE CHLORIDE ChromaDex Inc. (US) 2023-09-21 US disclosed
EP-2156182-B1 DETECTION OF AN ANALYTE IN A SAMPLE OF HEMOLYZED WHOLE BLOOD ROCHE DIAGNOSTICS GMBH (DE) 2010-10-06 EP disclosed
US-4631339-A 1,3,5-triazepinones ELI LILLY AND COMPANY (US) 1986-12-23 US disclosed
US-4514564-A 7β-(2'-(1\",3\",5\"-Triazepin-4\"-one)-2'-(oxime ether)-acetamido)-3-substituted cephalosporins ELI LILLY AND COMPANY (US) 1985-04-30 US disclosed
US-4436912-A 7-[2-(2-Aminooxazol-4-yl)-2-(oximino)acetamido cephalosporin antibiotics and intermediates therefor ELI LILLY AND COMPANY (US) 1984-03-13 US disclosed
US-4430499-A 7-[2-(2-Aminooxazol-4-yl)-2-(oximino)acetamido]cephalosporin antibiotics ELI LILLY AND COMPANY (US) 1984-02-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230295211-A1 METHODS OF PRODUCING CRYSTALLINE BETA NICOTINAMIDE RIBOSIDE TRIACETATE CHLORIDE NAMPT, NADK, ADH1B L3MBTL1 4005/4885NPSR1 3392/4885MAPT 766/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.