Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 6/20 | 0.41 |
| ▸ | PYGL | P06737 | 1/20 | 0.41 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GLB1 | P16278 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25827454 | 0.83 | — | — | |
| SCHEMBL14385385 | 0.83 | — | — | |
| SCHEMBL10918686 | 0.82 | GBA1 (0.35) | GBA1PYGLGBA2GAAGLB1 | |
| SCHEMBL10920685 | 0.80 | GBA1 (0.41) | GBA1PYGLGBA2GAAGLB1 | |
| SCHEMBL14256079 | 0.79 | EPHX2 (0.35) | GBA1PYGLGBA2GAAGLB1 | |
| SCHEMBL13167672 | 0.78 | INPP5A (0.31) | — | |
| SCHEMBL5228403 | 0.75 | CCR5 (0.32) | — | |
| SCHEMBL1547371 | 0.75 | CCR5 (0.32) | — | |
| SCHEMBL6984639 | 0.75 | CCR5 (0.32) | — | |
| SCHEMBL15632495 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0203902-A2 | 1,2,3,4,5,6-Hexahydro-azepino[4,5-b] indole derivatives, their preparation, intermediate compounds and their therapeutical use | OMNICHEM Société anonyme (BE) | 1986-12-03 | — | — | EP | disclosed |