Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 15/20 | 0.42 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10919443 | 0.79 | GPBAR1 (0.47) | PDE10AGPBAR1CYSLTR1ALOX5 | |
| SCHEMBL10547024 | 0.71 | PDE10A (0.49) | PDE10AGPBAR1CYSLTR1 | |
| SCHEMBL10546022 | 0.71 | GPBAR1 (0.65) | PDE10AGPBAR1CYSLTR1 | |
| SCHEMBL10543676 | 0.70 | PDE10A (0.57) | PDE10ACYSLTR1 | |
| SCHEMBL4388489 | 0.65 | PDE10A (0.79) | PDE10A | |
| SCHEMBL2840650 | 0.64 | PDE10A (0.63) | PDE10A | |
| SCHEMBL17384532 | 0.63 | CYSLTR1 (0.38) | CYSLTR1 | |
| SCHEMBL22901568 | 0.63 | MAPT (0.54) | — | |
| SCHEMBL20636307 | 0.62 | LTA4H (0.47) | — | |
| SCHEMBL4389390 | 0.62 | PDE10A (0.70) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4839369-A | ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | RORER PHARMACEUTICAL CORPORATION (US) | 1989-06-13 | — | — | US | disclosed |