SCHEMBL10920105

SCHEMBL10920105

CCC(CCN)=C(CC)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 9/20 0.49
CYP3A4 P08684 2/20 0.49
ESR1 P03372 12/20 0.47
ESR2 Q92731 9/20 0.47
CYP1A2 P05177 1/20 0.44
CYP2A6 P11509 1/20 0.44
CYP3A5 P20815 1/20 0.44
PTGS2 P35354 3/20 0.44
PGR P06401 1/20 0.41
ATM Q13315 1/20 0.41
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23641321 0.86 ESR1 (0.50) CYP19A1CYP3A4ESR1ESR2CYP1A2
SCHEMBL9310275 0.86 ESR1 (0.50) CYP19A1CYP3A4ESR1ESR2CYP1A2
SCHEMBL5278371 0.86 ESR1 (0.48) CYP19A1CYP3A4ESR1ESR2CYP1A2
SCHEMBL585024 0.85 ESR1 (0.55) CYP19A1CYP3A4ESR1ESR2CYP1A2
Hydrochloric Acid SCHEMBL28664967 0.81 ESR1 (0.52) CYP19A1CYP3A4ESR1ESR2CYP1A2
SCHEMBL9310053 0.79 PTGS2 (0.52) CYP19A1CYP3A4ESR1ESR2CYP1A2
SCHEMBL5278366 0.79 ESR1 (0.46) CYP19A1CYP3A4ESR1ESR2CYP1A2
SCHEMBL3314631 0.78 ESR1 (0.61) CYP19A1CYP3A4ESR1ESR2CYP1A2
SCHEMBL8596721 0.78 ESR1 (0.61) CYP19A1CYP3A4ESR1ESR2CYP1A2
SCHEMBL9310985 0.76 ESR1 (0.55) CYP19A1CYP3A4ESR1ESR2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-61227798-A None JP disclosed
JP-S61227798-A SEPARATION OF CELL TSURUTA TEIJI 1986-10-09 JP disclosed