Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9214119 | 1.00 | LMNA (0.46) | LMNAALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL10422598 | 1.00 | LMNA (0.46) | LMNAALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL10670559 | 0.98 | ALDH1A1 (0.43) | LMNAALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL6748206 | 0.91 | LMNA (0.46) | LMNAALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL163878 | 0.91 | LMNA (0.46) | LMNAALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL3338373 | 0.91 | ALDH1A1 (0.50) | LMNAALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL4655229 | 0.84 | ALDH1A1 (0.52) | LMNAALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL4275870 | 0.84 | LMNA (0.56) | LMNAALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL4268909 | 0.84 | LMNA (0.56) | LMNAALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL4273642 | 0.84 | LMNA (0.56) | LMNAALDH1A1TDP1TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4549992-A | Antihypertensive amides | USV PHARMACEUTICAL CORP. (US) | 1985-10-29 | — | — | US | disclosed |