Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.58 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10918490 | 0.82 | HSP90AA1 (0.60) | HSP90AA1ADORA2AADORA1ABCB1HTT | |
| SCHEMBL10920686 | 0.82 | HSP90AB1 (0.50) | HSP90AA1ADORA2AADORA1MEN1CYP1A2 | |
| SCHEMBL9846595 | 0.81 | HSP90AA1 (0.75) | HSP90AA1ADORA2AADORA1ABCB1HTT | |
| SCHEMBL10916068 | 0.81 | HSP90AA1 (0.75) | HSP90AA1ADORA2AADORA1ABCB1HTT | |
| SCHEMBL379319 | 0.81 | SMN1; SMN2 (0.46) | HTTTDP1MEN1CYP1A2KMT2A | |
| SCHEMBL1576984 | 0.81 | MEN1 (0.43) | TDP1MEN1CYP1A2KMT2ASMN1; SMN2 | |
| SCHEMBL9203436 | 0.77 | HSP90AA1 (0.53) | HSP90AA1ADORA2AADORA1ABCB1 | |
| SCHEMBL10921086 | 0.74 | MEN1 (0.44) | HSP90AA1HIF1AHTTTDP1MEN1 | |
| SCHEMBL10919233 | 0.74 | ALDH1A1 (0.44) | HSP90AA1ADORA2AADORA1HIF1AHTT | |
| SCHEMBL9202407 | 0.74 | HSP90AA1 (0.50) | HSP90AA1ADORA2AADORA1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174574-A2 | Fungicidal agents on the basis of triazine derivatives | BAYER AG (DE) | 1986-03-19 | — | — | EP | disclosed |