SCHEMBL379319

SCHEMBL379319

CCOc1nc(N)nc(N)n1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.46
LMNA P02545 2/20 0.46
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
CYP1A2 P05177 1/20 0.43
MAPK1 P28482 2/20 0.39
ALDH1A1 P00352 2/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
MAT2A P31153 1/20 0.38
KDM4E B2RXH2 1/20 0.38
HPGD P15428 1/20 0.38
TSHR P16473 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
POLB P06746 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
PDE4B Q07343 1/20 0.35
PDE4D Q08499 1/20 0.35
HTT P42858 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1576984 0.95 MEN1 (0.43) SMN1; SMN2LMNAMEN1KMT2ACYP1A2
SCHEMBL1131137 0.86 HSP90AA1 (0.44) SMN1; SMN2LMNAMEN1KMT2ACYP1A2
SCHEMBL10617774 0.86 PDE4B (0.42) SMN1; SMN2LMNAMEN1KMT2ACYP1A2
SCHEMBL13771720 0.84 HSP90AA1 (0.46) SMN1; SMN2LMNAMEN1KMT2ACYP1A2
SCHEMBL10920686 0.83 HSP90AB1 (0.50) SMN1; SMN2LMNAMEN1KMT2ACYP1A2
Pyrophosphoric Acid SCHEMBL17311813 0.82 SMN1; SMN2 (0.36) SMN1; SMN2LMNAMEN1KMT2ACYP1A2
SCHEMBL10921968 0.81 HSP90AA1 (0.58) SMN1; SMN2LMNAMEN1KMT2ACYP1A2
SCHEMBL1577386 0.81 MEN1 (0.47) SMN1; SMN2LMNAMEN1KMT2ACYP1A2
SCHEMBL379413 0.80 HSD17B10 (0.49) SMN1; SMN2LMNAMEN1KMT2ACYP1A2
SCHEMBL582039 0.80 MEN1 (0.52) SMN1; SMN2LMNAMEN1KMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4715001-A1 HORIZONTAL MEMBER FOR AUTOMOBILES AND METHOD FOR MANUFACTURING SAME TEIJIN LIMITED (JP) 2026-03-25 EP disclosed
EP-4083168-B1 FLAME RETARDANT COMPOSITION AND FLAME-RETARDANT THERMOPLASTIC RESIN COMPOSITION CONTAINING SAID FLAME RETARDANT COMPOSITION DAIHACHI CHEM IND (JP) 2026-02-18 EP disclosed
EP-3708636-B1 FLAME RETARDANT COMPOSITION AND FLAME-RETARDANT THERMOPLASTIC RESIN COMPOSITION CONTAINING SAID FLAME RETARDANT COMPOSITION DAIHACHI CHEM IND (JP) 2026-02-11 EP disclosed
US-20250388743-A1 PROPYLENE-BASED RESIN COMPOSITION AND MOLDED ARTICLE SUMITOMO CHEMICAL CO (JP) 2025-12-25 US disclosed
EP-4606842-A1 COMPOSITE SHEET, METHOD FOR PRODUCING COMPOSITE SHEET, AND MOLDED BODY Mitsubishi Chemical Corporation (JP) 2025-08-27 EP disclosed
EP-3943554-B1 PHOSPHATE AMINE SALT COMPOSITION AND THE USE AS FLAME RETARDANT ADEKA CORP (JP) 2025-08-27 EP disclosed
EP-4606843-A1 FIBER-REINFORCED RESIN COMPOSITE MATERIAL AND MOLDED BODY USING SAME Mitsubishi Chemical Corporation (JP) 2025-08-27 EP disclosed
EP-4606566-A1 LAMINATE Mitsubishi Chemical Corporation (JP) 2025-08-27 EP disclosed
EP-4606866-A1 RESIN COMPOSITION, METHOD FOR PRODUCING RESIN PRODUCT, AND FLAME RETARDANT MASTERBATCH Mitsubishi Chemical Corporation (JP) 2025-08-27 EP disclosed
US-20250242568-A1 LAMINATE MITSUBISHI CHEMICAL CORPORATION (JP) 2025-07-31 US disclosed
EP-2256161-A1 FLAME-RETARDANT CHLORINE-CONTAINING RESIN COMPOSITION Adeka Corporation (JP) 2010-12-01 EP disclosed
US-20050256234-A1 Flame retardant composition and flame retardant resin composition containing the composition ASAHI DENKA CO., LTD (JP) 2005-11-17 US disclosed
EP-1277794-B1 Flame-retardant resin composition ASAHI DENKA KOGYO KK (JP) 2005-04-06 EP disclosed
EP-1516907-A1 FLAME RETARDER COMPOSITION AND FLAME RETARDANT RESIN COMPOSITION CONTAINING THE COMPOSITION Asahi Denka Co., Ltd. (JP) 2005-03-23 EP disclosed
US-20030088000-A1 Flame-retardant resin composition ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 2003-05-08 US disclosed
EP-1277794-A1 Flame-retardant resin composition ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 2003-01-22 EP disclosed
EP-0751170-B1 Silicone derivatives, their production and use CHIBA FLOUR MILLING (JP) 2003-01-22 EP disclosed
US-5859243-A AMINOSILICONES HAVING PYRIMIDINYL GROUPS BOUND TO THE AMINO GROUPS; USED TO GEL SILICONE OIL OR TO INCREASE THE VISCOSITY STABLY AND HOMOGENEOUSLY; BASES FOR COSMETICS, DRUGS, INDUSTRIAL MATERIAL; FEEL; TEXTURE CHIBA FLOUR MILLING CO., LTD. (JP) 1999-01-12 US disclosed
US-5712391-A POLYSILOXANES MODIFIED WITH TRIAZINE GROUPS AND DIAMINE COMPOUNDS FOR COSMETICS CHIBA FLOUR MILLING CO., LTD. (JP) 1998-01-27 US disclosed
EP-0751170-A2 Silicone derivatives, their production and use Chiba Flour Milling Co., Ltd. (JP) 1997-01-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250388743-A1 PROPYLENE-BASED RESIN COMPOSITION AND MOLDED ARTICLE TAF1, PFN1, PAF1 SMN1; SMN2 2262/4885LMNA 1365/4885MEN1 4642/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.