Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PAM | P19021 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27643463 | 0.95 | TSHR (0.53) | TSHRALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL16439989 | 0.84 | TSHR (0.68) | TSHRALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL27643464 | 0.83 | TSHR (0.53) | TSHRALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL28774932 | 0.82 | CNR2 (0.51) | TSHRALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL4414630 | 0.81 | TSHR (0.59) | TSHRALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL28147494 | 0.80 | MMP8 (0.51) | TSHRALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL19483145 | 0.79 | ALDH1A1 (0.51) | TSHRALDH1A1MAPK1L3MBTL1KMT2A | |
| Phenylacetic Acid SCHEMBL28169172 | 0.79 | AKR1B1 (0.55) | TSHRALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL27139938 | 0.78 | TSHR (0.58) | TSHRALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL248113 | 0.78 | ALDH1A1 (0.65) | TSHRALDH1A1MAPK1L3MBTL1PAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4567291-A | ODORS, FLAVORS | GIVAUDAN CORPORATION (US) | 1986-01-28 | — | — | US | disclosed |
| US-4500729-A | ODORANT AND FLAVORS | GIVAUDAN CORPORATION (US) | 1985-02-19 | — | — | US | disclosed |
| US-4486337-A | ORGANOLEPTIC | GIVAUDAN CORPORATION (US) | 1984-12-04 | — | — | US | disclosed |