SCHEMBL10922158

SCHEMBL10922158

CCOC(=O)c1c(-c2cccc(F)n2)n[nH]c1S

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4D Q08499 1/20 0.43
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
CYP1A2 P05177 1/20 0.40
ADORA3 P0DMS8 3/20 0.39
HPGDS O60760 1/20 0.39
ADORA2B P29275 1/20 0.38
KDM4E B2RXH2 5/20 0.38
MAPT P10636 2/20 0.38
ALDH1A1 P00352 2/20 0.38
NPC1 O15118 1/20 0.38
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.38
HPGD P15428 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10924140 0.86 PDE4D (0.43) PDE4DCA12CA1CA2CA7
SCHEMBL10919608 0.81 LMNA (0.47) PDE4DCA12CA1CA2CA7
SCHEMBL9747984 0.80 MEN1 (0.42) PDE4DSMN1; SMN2ADORA3HPGDSKDM4E
SCHEMBL10925879 0.80 PDE4D (0.40) PDE4DCA12CA1CA2CA7
SCHEMBL10918781 0.75 PDE4D (0.40) PDE4DCA12CA1CA2CA7
SCHEMBL10922416 0.75 PDE4D (0.45) PDE4DCA12CA1CA2CA7
SCHEMBL9748822 0.74 KDM4E (0.44) SMN1; SMN2ADORA3HPGDSADORA2BKDM4E
SCHEMBL10921097 0.74 ALDH1A1 (0.49) PDE4DSMN1; SMN2ADORA3HPGDSKDM4E
SCHEMBL10921204 0.72 CA12 (0.42) PDE4DCA12CA1CA2CA7
SCHEMBL10920378 0.72 CA12 (0.42) PDE4DCA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0189069-A2 Pyrazolesulfonamide derivative, process for its production and herbicide containing it NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1986-07-30 EP disclosed