Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.39 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.39 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11639176 | 0.89 | THRB (0.48) | MAPTKDM4ENPC1ALDH1A1LMNA | |
| SCHEMBL9064624 | 0.88 | MAPT (0.44) | MAPTKDM4ENPC1ALDH1A1LMNA | |
| SCHEMBL11149394 | 0.86 | THRB (0.45) | MAPTKDM4ENPC1ALDH1A1LMNA | |
| SCHEMBL7563484 | 0.84 | MAPT (0.42) | MAPTKDM4ENPC1ALDH1A1LMNA | |
| SCHEMBL11635655 | 0.84 | THRB (0.45) | MAPTKDM4ENPC1ALDH1A1LMNA | |
| SCHEMBL7570836 | 0.84 | MAPT (0.42) | MAPTKDM4ENPC1ALDH1A1LMNA | |
| SCHEMBL9037391 | 0.83 | MAPT (0.54) | MAPTKDM4ENPC1ALDH1A1LMNA | |
| SCHEMBL10755571 | 0.83 | POLB (0.44) | MAPTALDH1A1THRBALKBH2ALKBH5 | |
| SCHEMBL10744629 | 0.82 | MAPT (0.46) | MAPTKDM4ENPC1ALDH1A1LMNA | |
| SCHEMBL10455416 | 0.82 | MAPT (0.46) | MAPTKDM4ENPC1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0009419-B1 | AGRICULTURAL SULFONAMIDES, AND PREPARATION AND USE THEREOF | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-01-02 | — | — | EP | claimed |
| US-4496754-A | Silyl carbamates and synthesis thereof | UNION CARBIDE CORPORATION (US) | 1985-01-29 | — | — | US | claimed |
| EP-0009419-A1 | Agricultural sulfonamides, and preparation and use thereof | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-04-02 | — | — | EP | claimed |
| EP-0009419-B1 | AGRICULTURAL SULFONAMIDES, AND PREPARATION AND USE THEREOF | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-01-02 | — | — | EP | disclosed |
| EP-0009419-A1 | Agricultural sulfonamides, and preparation and use thereof | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-04-02 | — | — | EP | disclosed |