Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7563484 | 0.99 | MAPT (0.42) | MAPTKDM4ENPC1ALDH1A1THRB | |
| SCHEMBL9064624 | 0.92 | MAPT (0.44) | MAPTKDM4ENPC1ALDH1A1THRB | |
| SCHEMBL11639176 | 0.87 | THRB (0.48) | MAPTKDM4ENPC1ALDH1A1THRB | |
| SCHEMBL11149394 | 0.86 | THRB (0.45) | MAPTKDM4ENPC1ALDH1A1THRB | |
| SCHEMBL11635655 | 0.84 | THRB (0.45) | MAPTKDM4ENPC1ALDH1A1THRB | |
| SCHEMBL10922201 | 0.84 | MAPT (0.48) | MAPTKDM4ENPC1ALDH1A1THRB | |
| SCHEMBL7562831 | 0.83 | MAPT (0.44) | MAPTKDM4ENPC1ALDH1A1CA1 | |
| SCHEMBL11153158 | 0.81 | SLC10A6 (0.42) | MAPTKDM4ENPC1ALDH1A1THRB | |
| SCHEMBL8874996 | 0.79 | GAA (0.53) | MAPTKDM4ETHRBPKMCA1 | |
| SCHEMBL11562116 | 0.78 | GAA (0.58) | MAPTTHRBPKMCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6413911-B1 | REACTING A SULFONYL ISOCYANATE WITH A 2-AMINO-1,3,5-TRIAZINE OR 2-AMINOPYRIMIDINE, OR REACTING A SULFONAMIDE WITH A PHENYL CARBAMATE OR ISOCYANATE OF -1,3,5-TRIAZINE OR PYRIDINE | BASF AKTIENGESELLSCHAFT (DE) | 2002-07-02 | — | — | US | disclosed |
| US-20020049321-A1 | Herbicidal sulfonylureas, their preparation and use | MAYER HORST (DE) | 2002-04-25 | — | — | US | disclosed |
| US-6320046-B1 | A 2-AMINO-1,3,5-TRIAZINE AS CHEMICAL INTERMEDIATE; HIGH SELECTIVITY IN SENSITIVE CROPS | BASF AKTIENGESELLSCHAFT (DE) | 2001-11-20 | — | — | US | disclosed |
| US-6043196-A | Herbicidal sulfonylureas, their preparation and use | BASF AKTIENGESELLSCHAFT (DE) | 2000-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020049321-A1 | Herbicidal sulfonylureas, their preparation and use | SLC5A1, DDT, SLC5A2 | MAPT 4842/4885KDM4E 2158/4885NPC1 2008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.