Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | HTT | P42858 | 4/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | THRB | P10828 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10922241 | 1.00 | ALDH1A1 (0.63) | ALDH1A1MAPTHTTNPSR1LMNA | |
| SCHEMBL11027336 | 0.92 | ALDH1A1 (0.58) | ALDH1A1MAPTHTTNPSR1LMNA | |
| SCHEMBL11027332 | 0.92 | ALDH1A1 (0.58) | ALDH1A1MAPTHTTNPSR1LMNA | |
| SCHEMBL7705031 | 0.82 | MAPT (0.49) | ALDH1A1MAPTHTTNPSR1LMNA | |
| SCHEMBL7705029 | 0.82 | MAPT (0.49) | ALDH1A1MAPTHTTNPSR1LMNA | |
| SCHEMBL9037753 | 0.81 | MAPT (0.54) | ALDH1A1MAPTHTTNPSR1LMNA | |
| SCHEMBL9227605 | 0.78 | ALDH1A1 (0.55) | ALDH1A1MAPTHTTNPSR1LMNA | |
| SCHEMBL9227599 | 0.78 | ALDH1A1 (0.55) | ALDH1A1MAPTHTTNPSR1LMNA | |
| SCHEMBL11465588 | 0.78 | MAPT (0.59) | ALDH1A1MAPTHTTLMNAHPGD | |
| SCHEMBL801553 | 0.78 | MAPT (0.59) | ALDH1A1MAPTHTTLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140335050-A1 | METHODS, COMPOSITIONS, AND KITS FOR THE TREATMENT OF CANCER | THE GENERAL HOSPITAL CORPORATION (US) | 2014-11-13 | — | — | US | disclosed |
| EP-0138349-B1 | 3-BENZOYL-2-MERCAPTOPROPIONIC ACID DERIVATIES | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1986-11-12 | — | — | EP | disclosed |
| US-4594197-A | 3-benzoyl-2-mercaptopropionic acid derivatives | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1986-06-10 | — | — | US | disclosed |
| EP-0138349-A1 | 3-Benzoyl-2-mercaptopropionic acid derivaties | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1985-04-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140335050-A1 | METHODS, COMPOSITIONS, AND KITS FOR THE TREATMENT OF CANCER | IL2RA, CD74, IL2 | ALDH1A1 1004/4885MAPT 3619/4885HTT 3894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.