Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.47 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7705031 | 1.00 | MAPT (0.49) | MAPTSMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL11027336 | 0.90 | ALDH1A1 (0.58) | MAPTSMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL11027332 | 0.90 | ALDH1A1 (0.58) | MAPTSMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL10922241 | 0.82 | ALDH1A1 (0.63) | MAPTSMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL10922239 | 0.82 | ALDH1A1 (0.63) | MAPTSMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL19193673 | 0.79 | MAPT (0.58) | MAPTSMN1; SMN2RAB9AALDH1A1LMNA | |
| SCHEMBL11465588 | 0.79 | MAPT (0.59) | MAPTSMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL801553 | 0.79 | MAPT (0.59) | MAPTSMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL1483722 | 0.79 | SMN1; SMN2 (0.52) | MAPTSMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL4905776 | 0.78 | SMN1; SMN2 (0.53) | MAPTSMN1; SMN2NPC1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102731722-A | Process for producing modified conjugated diene-based polymer, modified conjugated diene-based polymer, and polymer composition | SUMITOMO CHEMICAL CO | 2012-10-17 | — | — | CN | disclosed |
| US-RE37573-E1 | Process for the preparation of an olefin polymer using metallocenes containing specifically substituted indenyl ligands | BASELL POLYOLEFIN GMBH (DE) | 2002-03-05 | — | — | US | disclosed |
| US-5869584-A | Process for the preparation of an olefin polymer using metallocenes containing specifically substituted indenyl ligands | TARGOR GMBH (DE) | 1999-02-09 | — | — | US | disclosed |
| EP-0582194-B1 | Process for the preparation of polymers using metallocenes with specifically substituted indenyl ligands | TARGOR GMBH (DE) | 1998-05-06 | — | — | EP | disclosed |
| US-5455365-A | Metallocene compound containing substituted indenyl ligand and transition metal element from groups IVb, Vb, or VIb; addition polymerization with aluminoxane cocatalyst | HOECHST AG (DE) | 1995-10-03 | — | — | US | disclosed |
| EP-0582194-A1 | Process for the preparation of polymers using metallocenes with specifically substituted indenyl ligands | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-02-09 | — | — | EP | disclosed |