Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14611152 | 0.77 | LRRK2 (0.42) | BRD4HTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL629603 | 0.74 | PHLPP2 (0.38) | PTPN1BRD4HTTALDH1A1ENPP2 | |
| SCHEMBL7778665 | 0.73 | ALDH1A1 (0.48) | KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL10231835 | 0.71 | KMT2A (0.45) | BRD4HTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL14453590 | 0.71 | KMT2A (0.57) | BRD4TP53CREBBPHTTKMT2A | |
| SCHEMBL15423698 | 0.71 | SMN1; SMN2 (0.40) | HTTKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL13744288 | 0.70 | BRD4 (0.43) | PTPN1BRD4TP53CREBBPKMT2A | |
| SCHEMBL389605 | 0.69 | ALDH1A1 (0.52) | HTTKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL29466718 | 0.69 | ALDH1A1 (0.52) | HTTKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL10615326 | 0.69 | MAPT (0.42) | PTPN1BRD4TP53CREBBPKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4560746-A | MONOAZO DYES, 2-(2-QUINOLYL)-1,3-INDANEDIONESULFONIC ACID | THE HILTON-DAVIS CHEMICAL CO. (US) | 1985-12-24 | — | — | US | disclosed |