Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL629604 | 0.80 | ALDH1A1 (0.37) | SMN1; SMN2HTTALDH1A1LMNAENPP2 | |
| SCHEMBL14611152 | 0.75 | LRRK2 (0.42) | BRD4SMN1; SMN2HTTALDH1A1LMNA | |
| SCHEMBL14533129 | 0.74 | PHLPP2 (0.55) | PHLPP2BRD4PTPN1PTGS1PTGS2 | |
| SCHEMBL10922280 | 0.74 | PTPN1 (0.41) | BRD4PTPN1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL9813345 | 0.74 | TIMP3 (0.46) | PHLPP2SMN1; SMN2ALDH1A1LMNAPOLB | |
| SCHEMBL5471076 | 0.73 | PTPRC (0.32) | PTPN1ENPP2CASR | |
| SCHEMBL5471082 | 0.73 | PTPRC (0.32) | PTPN1ENPP2CASR | |
| SCHEMBL29878763 | 0.73 | PTPRC (0.32) | PTPN1ENPP2CASR | |
| SCHEMBL7778665 | 0.72 | ALDH1A1 (0.48) | ALDH1A1 | |
| SCHEMBL14453590 | 0.70 | KMT2A (0.57) | BRD4SMN1; SMN2HTTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2420538-A1 | PORPHYRAZINE DYE, INK COMPOSITION CONTAINING SAME, AND COLORED BODY | Nippon Kayaku Kabushiki Kaisha (JP) | 2012-02-22 | — | — | EP | disclosed |