Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.48 |
| ▸ | HTR1A | P08908 | 5/20 | 0.47 |
| ▸ | HTR3A | P46098 | 5/20 | 0.47 |
| ▸ | PRCP | P42785 | 1/20 | 0.45 |
| ▸ | PNMT | P11086 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | HTR2B | P41595 | 3/20 | 0.40 |
| ▸ | CD44 | P16070 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11038468 | 0.75 | ADRA2A (0.51) | MAOB | |
| SCHEMBL10701614 | 0.70 | HTR2C (0.55) | HTR2CHTR1AHTR3APNMTHTR2A | |
| SCHEMBL11407282 | 0.70 | HTR2C (0.40) | HTR2CPRCPPNMTHTR2AHTR2B | |
| SCHEMBL9101041 | 0.69 | KDM4E (0.46) | HTR1AHTR3APNMTHTR2B | |
| SCHEMBL10704701 | 0.69 | HTR2C (0.50) | HTR2CHTR1AHTR3AHTR2AHTR2B | |
| SCHEMBL9810170 | 0.69 | SRC (0.42) | HTR2CHTR1AHTR3A | |
| SCHEMBL175146 | 0.69 | HTR2C (1.00) | HTR2CPRCPPNMTHTR2AHTR2B | |
| SCHEMBL24265323 | 0.67 | HTR2C (0.56) | HTR2CPRCPPNMTHTR2AHTR2B | |
| SCHEMBL20880753 | 0.67 | HTR2C (0.54) | HTR2CPRCPPNMTHTR2AHTR2B | |
| SCHEMBL509247 | 0.67 | CD44 (0.75) | HTR2CPRCPPNMTHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0080012-B1 | 6-CHLORO-3-METHYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE, ITS ACID ADDITION SALTS AND ITS USE AS AN INTERMEDIATE | SMITHKLINE BECKMAN CORPORATION (US) | 1986-04-09 | — | — | EP | disclosed |