Sugi Predict

Sugi Predict / Compounds / SCHEMBL9810170

SCHEMBL9810170

SCHEMBL9810170

c1ccc(Sc2cccc3c2NCCC3)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SRC P12931 1/20 0.42
▸ HTR1A P08908 3/20 0.40
▸ HTR3A P46098 3/20 0.40
▸ CHRNA7 P36544 2/20 0.36
▸ KDM4E B2RXH2 1/20 0.36
▸ NSD2 O96028 1/20 0.36
▸ MAPT P10636 1/20 0.36
▸ MAPK1 P28482 1/20 0.36
▸ SLC13A5 Q86YT5 1/20 0.34
▸ TUBB4A P04350 1/20 0.33
▸ TUBB P07437 1/20 0.33
▸ TUBA3C P0DPH7 1/20 0.33
▸ TUBA1B P68363 1/20 0.33
▸ TUBA4A P68366 1/20 0.33
▸ TUBB4B P68371 1/20 0.33
▸ TUBB3 Q13509 1/20 0.33
▸ TUBB2A Q13885 1/20 0.33
▸ TUBB8 Q3ZCM7 1/20 0.33
▸ TUBA3E Q6PEY2 1/20 0.33
▸ TUBA1A Q71U36 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31222346 0.81 HTR1A (0.38) SRCHTR1AHTR3ACHRNA7KDM4E
SCHEMBL6359546 0.72 SRC (0.53) SRCKDM4EMAPTSLC13A5TSHR
SCHEMBL6300471 0.71 SLC13A5 (0.52) SRCHTR1ASLC13A5TSHR
SCHEMBL31222319 0.71 HTR1A (0.40) HTR1AHTR3ACHRNA7TUBB4ATUBB
SCHEMBL10841336 0.71 SMN1; SMN2 (0.35) HTR1AHTR3ACHRNA7KDM4ENSD2
SCHEMBL10922860 0.69 HTR2C (0.48) HTR1AHTR3AHTR2C
SCHEMBL1082367 0.68 SRC (0.49) SRCKDM4EMAPTSLC13A5TSHR
SCHEMBL13977383 0.68 SRC (0.49) SRCKDM4EMAPTSLC13A5TSHR
SCHEMBL327043 0.68 SRC (0.53) SRCKDM4EMAPTSLC13A5TSHR
SCHEMBL17969105 0.68 SRC (0.49) SRCKDM4EMAPTSLC13A5TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0254611-B1 DERIVATIVES OF 8-PHENYLTHIOTETRAHYDROQUINOLINES AND THEIR SALTS, THEIR SYNTHESIS FOR USE AS MEDICAMENTS AND COMPOSITIONS CONTAINING THEM ROUSSEL-UCLAF (FR) 1991-06-12 — — EP claimed
US-4847268-A 8-phenylthio-tetrahydroquinolines and anti-allergic use thereof ROUSSEL UCLAF (FR) 1989-07-11 — — US claimed
EP-0254611-A1 Derivatives of 8-phenylthiotetrahydroquinolines and their salts, their synthesis for use as medicaments and compositions containing them ROUSSEL-UCLAF (FR) 1988-01-27 — — EP claimed
EP-0254611-B1 DERIVATIVES OF 8-PHENYLTHIOTETRAHYDROQUINOLINES AND THEIR SALTS, THEIR SYNTHESIS FOR USE AS MEDICAMENTS AND COMPOSITIONS CONTAINING THEM ROUSSEL-UCLAF (FR) 1991-06-12 — — EP disclosed
EP-0254611-B1 DERIVATIVES OF 8-PHENYLTHIOTETRAHYDROQUINOLINES AND THEIR SALTS, THEIR SYNTHESIS FOR USE AS MEDICAMENTS AND COMPOSITIONS CONTAINING THEM ROUSSEL-UCLAF (FR) 1991-06-12 — — EP disclosed
US-4847268-A 8-phenylthio-tetrahydroquinolines and anti-allergic use thereof ROUSSEL UCLAF (FR) 1989-07-11 — — US disclosed
US-4847268-A 8-phenylthio-tetrahydroquinolines and anti-allergic use thereof ROUSSEL UCLAF (FR) 1989-07-11 — — US disclosed
US-4847268-A 8-phenylthio-tetrahydroquinolines and anti-allergic use thereof ROUSSEL UCLAF (FR) 1989-07-11 — — US disclosed
EP-0254611-A1 Derivatives of 8-phenylthiotetrahydroquinolines and their salts, their synthesis for use as medicaments and compositions containing them ROUSSEL-UCLAF (FR) 1988-01-27 — — EP disclosed
EP-0254611-A1 Derivatives of 8-phenylthiotetrahydroquinolines and their salts, their synthesis for use as medicaments and compositions containing them ROUSSEL-UCLAF (FR) 1988-01-27 — — EP disclosed
EP-0254611-A1 Derivatives of 8-phenylthiotetrahydroquinolines and their salts, their synthesis for use as medicaments and compositions containing them ROUSSEL-UCLAF (FR) 1988-01-27 — — EP disclosed
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