Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.53 |
| ▸ | PARP11 | Q9NR21 | 3/20 | 0.53 |
| ▸ | PARP1 | P09874 | 3/20 | 0.53 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20539302 | 0.87 | NOTUM (0.47) | PARP10PARP11PARP1BRD4KDM1A | |
| SCHEMBL30916119 | 0.87 | NOTUM (0.47) | PARP10PARP11PARP1BRD4KDM1A | |
| SCHEMBL1031349 | 0.83 | PARP1 (0.56) | PARP10PARP11PARP1BRD4KDM1A | |
| Hydrochloric Acid SCHEMBL2260204 | 0.81 | PARP1 (0.55) | PARP10PARP11PARP1BRD4KDM1A | |
| SCHEMBL15311783 | 0.79 | NISCH (0.42) | PARP10PARP11PARP1NISCHHTR7 | |
| SCHEMBL10921066 | 0.79 | NOTUM (0.50) | PARP10PARP11PARP1HTR7BCHE | |
| SCHEMBL24600039 | 0.78 | PARP10 (0.41) | PARP10PARP11PARP1BRD4KDM1A | |
| SCHEMBL10201715 | 0.78 | PARP1 (0.41) | PARP10PARP11PARP1BRD4BCHE | |
| SCHEMBL15312032 | 0.78 | HTR7 (0.46) | HTR7BRD4 | |
| SCHEMBL4718535 | 0.78 | PARP10 (0.64) | PARP10PARP11PARP1NISCHBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0089426-B1 | 2-AMINO-6-BIPHENYLACETIC ACIDS | A.H. ROBINS COMPANY, INCORPORATED (US) | 1986-06-11 | — | — | EP | disclosed |