SCHEMBL1031349

SCHEMBL1031349

Cc1cccc2c1CCN2

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 3/20 0.56
PARP10 Q53GL7 3/20 0.56
PARP11 Q9NR21 3/20 0.56
NOTUM Q6P988 1/20 0.44
HTR5A P47898 1/20 0.41
HTR1D P28221 1/20 0.38
NUDT1 P36639 1/20 0.38
BRD4 O60885 2/20 0.38
KDM1A O60341 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2260204 0.98 PARP1 (0.55) PARP1PARP10PARP11NOTUMHTR5A
SCHEMBL30826409 0.89 NUDT1 (0.47) PARP1PARP10PARP11HTR5AHTR1D
SCHEMBL5757236 0.89 NUDT1 (0.47) PARP1PARP10PARP11HTR5AHTR1D
SCHEMBL6221804 0.88 PARP1 (0.44) PARP1PARP10PARP11HTR5AHTR1D
SCHEMBL31170775 0.88 PARP1 (0.44) PARP1PARP10PARP11HTR5AHTR1D
SCHEMBL10923036 0.83 PARP10 (0.53) PARP1PARP10PARP11NOTUMNUDT1
SCHEMBL30916119 0.77 NOTUM (0.47) PARP1PARP10PARP11NOTUMBRD4
SCHEMBL20539302 0.77 NOTUM (0.47) PARP1PARP10PARP11NOTUMBRD4
SCHEMBL20777511 0.77 HTR5A (0.52) PARP1PARP10PARP11NOTUMHTR5A
SCHEMBL22326634 0.75 NOTUM (0.41) PARP1PARP10PARP11NOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 215 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4722187-A1 BUILDING BLOCK FOR TRIFLUOROALKYLATION AND TRIFLUOROALKYLATION METHOD USING SAME Seoul National University Hospital (KR) 2026-04-08 EP claimed
WO-2024242479-A1 BUILDING BLOCK FOR TRIFLUOROALKYLATION AND TRIFLUOROALKYLATION METHOD USING SAME 서울대학교병원 2024-11-28 WO claimed
US-20260125367-A1 CANCER TREATMENTS TARGETING CANCER STEM CELLS REMEDY PLAN, INC. (US) 2026-05-07 US disclosed
EP-4722187-A1 BUILDING BLOCK FOR TRIFLUOROALKYLATION AND TRIFLUOROALKYLATION METHOD USING SAME Seoul National University Hospital (KR) 2026-04-08 EP disclosed
US-12522587-B2 Cancer treatments targeting cancer stem cells REMEDY PLAN, INC. (US) 2026-01-13 US disclosed
US-20250171420-A1 MOLECULAR GLUE DEGRADERS AND METHODS OF USING THE SAME MONTE ROSA THERAPEUTICS AG (CH) 2025-05-29 US disclosed
EP-4540240-A1 MOLECULAR GLUE DEGRADERS AND METHODS OF USING THE SAME Monte Rosa Therapeutics AG (CH) 2025-04-23 EP disclosed
CN-113227054-B ROCK kinase inhibitors 切尔韦洛治疗有限责任公司 2025-04-11 CN disclosed
CN-119775198-A Cancer therapy targeting cancer stem cells 治疗方案股份有限公司 2025-04-08 CN disclosed
WO-2024242479-A1 BUILDING BLOCK FOR TRIFLUOROALKYLATION AND TRIFLUOROALKYLATION METHOD USING SAME 서울대학교병원 2024-11-28 WO disclosed
CN-112312899-B Cancer therapy targeting cancer stem cells 治疗方案股份有限公司 2024-11-22 CN disclosed
CN-1138042-A Antimigraine 1,2,5-thiadiazole derivatives of indolylalkyl-pyridinyl and pyrimidinylpiperazines BRISTOL MYERS SQUIBB CO (US) 1996-12-18 CN disclosed
EP-0746554-A1 4-HETEROCYCLYL-SUBSTITUTED QUINAZOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS ANTI-CANCER AGENTS PFIZER INC. (US) 1996-12-11 EP disclosed
EP-0729958-A2 Antimigraine 1,2,5-thiadiazole derivatives of indolylalkyl-pyridinyl and pyrimidinyl-piperazines BRISTOL-MYERS SQUIBB COMPANY (US) 1996-09-04 EP disclosed
US-5521188-A Antimigraine cyclobutenedione derivatives of indolylalkyl-pyridinyl and pyrimidinylpiperazines BRISTOL-MYERS SQUIBB COMPANY (US) 1996-05-28 US disclosed
CN-1112561-A Antimigraine cyclobutenedione derivatives of indolylalkyl-pyridinyl and pyrimidinylpiperazines BRISTOL MYERS SQUIBB CO (US) 1995-11-29 CN disclosed
WO-1995023141-A1 4-HETEROCYCLYL-SUBSTITUTED QUINAZOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS ANTI-CANCER AGENTS PFIZER INC. (US) 1995-08-31 WO disclosed
EP-0645385-A1 Antimigraine cyclobutenedione derivatives of indolylalkyl-pyridinyl and pyrimidinylpiperazines Bristol-Myers Squibb Company (US) 1995-03-29 EP disclosed
US-5047539-A Ultraviolet radiation stabilizers BASF AKTIENGESELLSCHAFT (DE) 1991-09-10 US disclosed
EP-0399278-A2 Heterocyclic amidine derivatives BASF Aktiengesellschaft (DE) 1990-11-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125367-A1 CANCER TREATMENTS TARGETING CANCER STEM CELLS MCL1, MALT1, BCL6 PARP1 474/4885PARP10 3986/4885PARP11 842/4885
US-20250171420-A1 MOLECULAR GLUE DEGRADERS AND METHODS OF USING THE SAME PSMA1, CSNK1G1, CSNK1A1 PARP1 307/4885PARP10 705/4885PARP11 319/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.