Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10926559 | 0.94 | SELP (0.39) | TP53TBXAS1TBXA2R | |
| SCHEMBL7513748 | 0.89 | MAPT (0.43) | TBXAS1TBXA2RMAPT | |
| SCHEMBL10922047 | 0.84 | CHRM5 (0.40) | TBXAS1TBXA2R | |
| SCHEMBL10923566 | 0.81 | TBXA2R (0.52) | TBXAS1TBXA2R | |
| SCHEMBL9749953 | 0.81 | TBXAS1 (0.37) | TBXAS1 | |
| SCHEMBL7518917 | 0.79 | PARP1 (0.41) | TBXAS1TBXA2RPOLBMAPTTDP1 | |
| SCHEMBL10563521 | 0.79 | TSHR (0.47) | TBXAS1TBXA2R | |
| SCHEMBL10565563 | 0.79 | AKR1B1 (0.57) | TBXAS1TBXA2R | |
| SCHEMBL4009695 | 0.79 | MAPT (0.43) | TBXAS1TBXA2RMAPT | |
| SCHEMBL10562607 | 0.79 | MAPT (0.43) | TBXAS1TBXA2RMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0188802-A2 | Dibenz (b,e) oxepin derivative and antiallergic agent | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1986-07-30 | — | — | EP | disclosed |