Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 3/20 | 0.68 |
| ▸ | NOS3 | P29474 | 2/20 | 0.68 |
| ▸ | NOS1 | P29475 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 9/20 | 0.62 |
| ▸ | NPC1 | O15118 | 8/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | CYP2E1 | P05181 | 5/20 | 0.56 |
| ▸ | CYP2C8 | P10632 | 5/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.56 |
| ▸ | CYP2B6 | P20813 | 5/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.50 |
| ▸ | RELA | Q04206 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10921495 | 0.91 | NOS2 (0.73) | NOS2NOS3NOS1RAB9ANPC1 | |
| SCHEMBL6881221 | 0.82 | NOS2 (0.72) | NOS2NOS3NOS1RAB9ANPC1 | |
| SCHEMBL10920878 | 0.81 | SMN1; SMN2 (0.58) | NOS2NOS3NOS1RAB9ANPC1 | |
| SCHEMBL10917609 | 0.80 | NOS2 (0.58) | NOS2NOS3NOS1RAB9ANPC1 | |
| SCHEMBL10917615 | 0.80 | NOS2 (0.58) | NOS2NOS3NOS1RAB9ALMNA | |
| SCHEMBL10921896 | 0.80 | NOS2 (0.55) | NOS2NOS3NOS1RAB9ANPC1 | |
| SCHEMBL10921902 | 0.80 | NOS2 (0.55) | NOS2NOS3NOS1RAB9ANPC1 | |
| SCHEMBL6882863 | 0.80 | NOS2 (0.69) | NOS2NOS3NOS1RAB9ANPC1 | |
| SCHEMBL2998260 | 0.80 | NOS2 (0.76) | NOS2NOS3NOS1RAB9ANPC1 | |
| SCHEMBL6378263 | 0.79 | NOS2 (0.68) | NOS2NOS3NOS1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0167943-A2 | Benzimidazole derivatives, process for their preparation, and their use as pharmaceuticals | BEECHAM GROUP PLC (GB) | 1986-01-15 | — | — | EP | disclosed |