Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.60 |
| ▸ | DRD4 | P21917 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | LSS | P48449 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3489540 | 0.89 | SIGMAR1 (0.60) | SIGMAR1DRD4ALDH1A1KDM4EMAPT | |
| SCHEMBL4681104 | 0.82 | SLC6A4 (0.43) | SIGMAR1DRD4MEN1KMT2AALDH1A1 | |
| SCHEMBL4681112 | 0.82 | SLC6A4 (0.43) | SIGMAR1DRD4MEN1KMT2AALDH1A1 | |
| SCHEMBL10926737 | 0.81 | DRD4 (0.50) | SIGMAR1DRD4KMT2AALDH1A1KDM4E | |
| SCHEMBL8961761 | 0.78 | MAPT (0.31) | MAPTSMN1; SMN2GAA | |
| SCHEMBL10925889 | 0.78 | SIGMAR1 (0.58) | SIGMAR1DRD4ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL5540026 | 0.76 | ACHE (0.60) | MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL8421218 | 0.76 | KDM4E (0.62) | DRD4MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL16993800 | 0.76 | CHRNA7 (0.55) | SIGMAR1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL4649494 | 0.76 | DRD4 (0.87) | SIGMAR1DRD4MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0076996-B1 | CARBOXYLIC-ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1986-01-02 | — | — | EP | disclosed |