Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.63 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MMP12 | P39900 | 1/20 | 0.54 |
| ▸ | PARP1 | P09874 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10923658 | 0.90 | PDE3B (0.55) | MAPTRXFP1POLBALDH1A1KDM4E | |
| SCHEMBL3874578 | 0.83 | MMP12 (0.59) | MAPTRXFP1POLBALDH1A1KDM4E | |
| SCHEMBL705600 | 0.79 | MAPT (0.64) | MAPTRXFP1POLBALDH1A1KDM4E | |
| SCHEMBL4178218 | 0.78 | MMP12 (0.52) | MAPTRXFP1POLBALDH1A1KDM4E | |
| SCHEMBL28778400 | 0.78 | MMP12 (0.59) | MAPTRXFP1POLBALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL28979253 | 0.77 | AOC3 (0.64) | MAPTRXFP1POLBALDH1A1KDM4E | |
| SCHEMBL7844474 | 0.77 | MMP12 (0.51) | MAPTRXFP1POLBALDH1A1KDM4E | |
| SCHEMBL29248122 | 0.77 | HTR1A (0.58) | MAPTRXFP1POLBALDH1A1KDM4E | |
| SCHEMBL4187398 | 0.77 | HTR1A (0.53) | MAPTRXFP1POLBALDH1A1KDM4E | |
| SCHEMBL4187181 | 0.77 | HTR1A (0.58) | MAPTRXFP1POLBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171702-A1 | Benzoxazinone derivatives, preparation and use | BEECHAM GROUP PLC (GB) | 1986-02-19 | — | — | EP | disclosed |