Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | EGFR | P00533 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | NPY1R | P25929 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.57 |
| ▸ | LTA4H | P09960 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10922970 | 1.00 | RAB9A (0.61) | RAB9ANPC1SMN1; SMN2HTTKDM4E | |
| Bromide SCHEMBL10552927 | 0.99 | NPC1 (0.60) | RAB9ANPC1SMN1; SMN2HTTKDM4E | |
| Bromide SCHEMBL10559709 | 0.99 | NPC1 (0.60) | RAB9ANPC1SMN1; SMN2HTTKDM4E | |
| SCHEMBL10926912 | 0.99 | HTT (0.61) | RAB9ANPC1SMN1; SMN2HTTKDM4E | |
| Bromide SCHEMBL10553706 | 0.98 | HTT (0.60) | RAB9ANPC1SMN1; SMN2HTTKDM4E | |
| SCHEMBL10924472 | 0.84 | ALOX5 (0.48) | RAB9ANPC1SMN1; SMN2HTTKDM4E | |
| Bromide SCHEMBL10553174 | 0.84 | ALOX5 (0.47) | RAB9ANPC1SMN1; SMN2HTTKDM4E | |
| SCHEMBL7231255 | 0.83 | NPC1 (0.54) | RAB9ANPC1SMN1; SMN2HTTKDM4E | |
| SCHEMBL10921355 | 0.83 | KDM4E (0.48) | RAB9ANPC1SMN1; SMN2HTTKDM4E | |
| Bromide SCHEMBL10556871 | 0.82 | KDM4E (0.47) | RAB9ANPC1SMN1; SMN2HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0180994-A2 | Antihypertensive dialkyl aminoethylaniline derivatives | SYNTEX (U.S.A.) INC. (US) | 1986-05-14 | — | — | EP | disclosed |