Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MAP2 | P11137 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 2/20 | 0.41 |
| ▸ | SI | P14410 | 2/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10924963 | 0.89 | EGFR (0.51) | PPARGEGFRSRCGAAMAPT | |
| SCHEMBL10923170 | 0.87 | CSF1R (0.44) | PTGDR2CSF1RTHRBMAP2GAA | |
| SCHEMBL10832252 | 0.85 | HTR6 (0.49) | CSF1RGAAMGAMSIMGAM2 | |
| SCHEMBL10832255 | 0.85 | HTR6 (0.46) | CSF1RGAAMGAMSIMGAM2 | |
| SCHEMBL10922515 | 0.83 | CYP1A2 (0.44) | PTGDR2CSF1RTHRBGAAMGAM | |
| SCHEMBL10832434 | 0.82 | GAA (0.47) | PTGDR2CSF1RMAP2GAATSHR | |
| SCHEMBL6929600 | 0.81 | PPARG (0.66) | PPARGTACR1EGFRMAP2SRC | |
| SCHEMBL10831709 | 0.80 | MAPT (0.43) | PTGDR2CSF1RTHRBMAP2GAA | |
| SCHEMBL10924718 | 0.80 | CSF1R (0.44) | PTGDR2CSF1RTHRBMAP2GAA | |
| SCHEMBL11054385 | 0.80 | CSF1R (0.46) | PTGDR2CSF1RMAP2GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4536499-A | Isoxazolyl indolamines having anti-diabetic activity | SANDOZ, INC. (US) | 1985-08-20 | — | — | US | disclosed |