Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10925087 | 1.00 | ALDH1A1 (0.40) | ALDH1A1MAPTTRPA1NPSR1GLO1 | |
| SCHEMBL15341146 | 0.84 | ALDH1A1 (0.39) | ALDH1A1MAPTTRPA1NPSR1GLO1 | |
| SCHEMBL15396187 | 0.83 | MAPT (0.37) | ALDH1A1MAPTTRPA1NPSR1GLO1 | |
| SCHEMBL21325798 | 0.83 | ALOX15 (0.39) | ALDH1A1MAPTTRPA1NPSR1GLO1 | |
| SCHEMBL15344247 | 0.79 | MAPT (0.43) | ALDH1A1MAPTNPSR1GLO1LMNA | |
| SCHEMBL12482162 | 0.79 | MAPT (0.43) | ALDH1A1MAPTNPSR1GLO1LMNA | |
| SCHEMBL15333978 | 0.79 | MAPT (0.43) | ALDH1A1MAPTNPSR1GLO1LMNA | |
| SCHEMBL2914885 | 0.73 | ALDH1A1 (0.46) | ALDH1A1MAPTTRPA1NPSR1GLO1 | |
| SCHEMBL15396130 | 0.73 | MAPT (0.44) | ALDH1A1MAPTLMNAHSD17B10GAA | |
| SCHEMBL6077631 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4551472-A | Unsymmetrical bis-carbamate compounds | UNION CARBIDE CORPORATION (US) | 1985-11-05 | — | — | US | disclosed |