Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10928298 | 0.81 | KDM4E (0.49) | TP53ALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL10922551 | 0.80 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL10921232 | 0.78 | CDC7 (0.47) | ALDH1A1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL10918426 | 0.76 | GRM6 (0.42) | TP53MDM2ALDH1A1MEN1KMT2A | |
| SCHEMBL1776503 | 0.76 | GABRA5 (0.53) | TP53ALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL30592812 | 0.76 | GABRA5 (0.53) | TP53ALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL9748942 | 0.75 | KDM4E (0.43) | TP53ALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL10918731 | 0.75 | MAPT (0.40) | ALPLALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL10922835 | 0.75 | SMN1; SMN2 (0.40) | TP53MDM2ALDH1A1MEN1KMT2A | |
| SCHEMBL10920378 | 0.75 | CA12 (0.42) | TP53ALDH1A1MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0114045-B1 | PYRIMIDINE DERIVATIVES AND THEIR USE AS PESTICIDES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1986-09-03 | — | — | EP | claimed |