Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 5/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.51 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 2/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10926731 | 0.87 | MAPT (0.68) | S1PR1S1PR3S1PR2MAPTRXFP1 | |
| SCHEMBL10925065 | 0.85 | MAPT (0.54) | S1PR1S1PR3S1PR2MAPTRXFP1 | |
| SCHEMBL5809402 | 0.85 | MAPT (0.54) | S1PR1S1PR3S1PR2MAPTRXFP1 | |
| SCHEMBL9860436 | 0.84 | MAPT (0.69) | S1PR1S1PR3S1PR2MAPTRXFP1 | |
| SCHEMBL2835656 | 0.84 | MAPT (0.69) | S1PR1S1PR3S1PR2MAPTRXFP1 | |
| SCHEMBL25575670 | 0.84 | MAPT (0.69) | S1PR1S1PR3S1PR2MAPTRXFP1 | |
| Iocanlidic Acid SCHEMBL290025 | 0.84 | MAPT (0.69) | S1PR1S1PR3S1PR2MAPTRXFP1 | |
| SCHEMBL2197174 | 0.82 | MAPT (0.66) | S1PR1S1PR3S1PR2MAPTRXFP1 | |
| SCHEMBL10925462 | 0.82 | MAPT (0.50) | S1PR1S1PR3S1PR2MAPTRXFP1 | |
| SCHEMBL7783334 | 0.79 | ALDH1A1 (0.66) | MAPTALDH1A1HSD17B10FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153403-A4 | CHEMICAL COMPOUNDS. | MALLINCKRODT INC (US) | 1985-12-11 | — | — | EP | disclosed |
| EP-0153403-A1 | CHEMICAL COMPOUNDS | Mallinckrodt, Inc. (a Delaware corporation) (US) | 1985-09-04 | — | — | EP | disclosed |
| WO-1985000753-A1 | CHEMICAL COMPOUNDS | MALLINCKRODT, INC. (US) | 1985-02-28 | — | — | WO | disclosed |