Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 1/20 | 0.53 |
| ▸ | SYK | P43405 | 4/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.48 |
| ▸ | INCENP | Q9NQS7 | 2/20 | 0.48 |
| ▸ | DHFR | P00374 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10922053 | 0.83 | CHEK1 (0.50) | DHFRALDH1A1CD274HTR2CCYP1A2 | |
| SCHEMBL30025932 | 0.82 | HTR2C (0.50) | KDM4EALDH1A1HPGDHTR2AHTR2C | |
| SCHEMBL550150 | 0.82 | HTR2C (0.50) | KDM4EALDH1A1HPGDHTR2AHTR2C | |
| SCHEMBL10711490 | 0.76 | TDP2 (0.75) | TDP2DHFRHDAC4HDAC2HDAC8 | |
| SCHEMBL29899709 | 0.75 | CA12 (0.60) | TDP2SYKDHFRHDAC4HDAC2 | |
| Acetic Acid SCHEMBL10992625 | 0.74 | CPS1 (0.48) | KDM4EHTR2AHTR2CHTR2BMAPKAPK2 | |
| SCHEMBL8503322 | 0.73 | CA12 (0.65) | TDP2SYKDHFRHDAC4HDAC2 | |
| SCHEMBL6163752 | 0.73 | KDM4E (0.60) | TDP2SYKDHFRHDAC4HDAC2 | |
| SCHEMBL1395133 | 0.72 | HRH3 (0.52) | TLR9TLR8TLR7HTR2AHTR2C | |
| SCHEMBL30471897 | 0.72 | HRH3 (0.52) | TLR9TLR8TLR7HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0089426-B1 | 2-AMINO-6-BIPHENYLACETIC ACIDS | A.H. ROBINS COMPANY, INCORPORATED (US) | 1986-06-11 | — | — | EP | disclosed |