SCHEMBL109265

SCHEMBL109265

FC(OCC1CO1)C(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.40
TSHR P16473 5/20 0.38
MAPK1 P28482 1/20 0.38
TDP1 Q9NUW8 2/20 0.35
TP53 P04637 3/20 0.34
HIF1A Q16665 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
CYP3A4 P08684 1/20 0.34
MAPT P10636 2/20 0.34
HPGD P15428 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
CYP1A2 P05177 1/20 0.34
PPARG P37231 1/20 0.34
GLA P06280 1/20 0.32
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.31
PKM P14618 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10938819 0.83 ALDH1A1 (0.38) ALDH1A1TSHRMAPK1TDP1TP53
SCHEMBL10943101 0.82 ALDH1A1 (0.36) ALDH1A1TSHRMAPK1TDP1TP53
SCHEMBL1071671 0.80 ALDH1A1 (0.35) ALDH1A1TSHRMAPK1TDP1TP53
SCHEMBL11942394 0.80 ALDH1A1 (0.41) ALDH1A1TSHRMAPK1TDP1TP53
SCHEMBL709623 0.79 ALDH1A1 (0.34) ALDH1A1TSHRMAPK1TDP1TP53
SCHEMBL9513874 0.79 TSHR (0.35) ALDH1A1TSHRMAPK1TDP1TP53
SCHEMBL6911632 0.77 ALDH1A1 (0.33) ALDH1A1TSHRMAPK1TDP1
SCHEMBL6243102 0.77 ALDH1A1 (0.33) ALDH1A1TSHRMAPK1TDP1
SCHEMBL1130097 0.77 TSHR (0.50) ALDH1A1TSHRMAPK1TDP1TP53
SCHEMBL711179 0.76 ALDH1A1 (0.32) ALDH1A1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9187691-B2 Particles Life Technologies Corporation (US) 2015-11-17 US claimed
US-8697453-B2 Particles LIFE TECHNOLOGIES AS (NO) 2014-04-15 US claimed
US-20130099151-A1 PARTICLES Life Technologies Corporation (US) 2013-04-25 US claimed
EP-2051075-B1 Use of superparamagnetic crystals to catalyse polymerisation of epoxide monomers INVITROGEN DYNAL AS (NO) 2011-08-03 EP claimed
EP-2051075-A1 Particles Invitrogen Dynal AS (NO) 2009-04-22 EP claimed
EP-3872101-B1 POLYMERIC PARTICLES LIFE TECH AS (NO) 2025-08-20 EP disclosed
CN-116640245-B Polymer particles 生命科技公司 2024-12-31 CN disclosed
US-20230340578-A1 SPATIAL ANALYSIS OF MULTIPLE TARGETS IN TISSUE SAMPLES Roche Sequencing Solutions, Inc. 2023-10-26 US disclosed
US-20230272127-A1 POLYMERIC PARTICLES LIFE TECHNOLOGIES AS (NO) 2023-08-31 US disclosed
CN-116640245-A polymer particles 生命科技公司 2023-08-25 CN disclosed
US-11680113-B2 Polymeric particles LIFE TECHNOLOGIES AS (NO) 2023-06-20 US disclosed
CN-110312742-B Polymer particles 生命科技公司 2023-05-12 CN disclosed
US-7211553-B2 Processing of substrates with dense fluids comprising acetylenic diols and/or alcohols AIR PRODUCTS AND CHEMICALS, INC. (US) 2007-05-01 US disclosed
US-20060131542-A1 Particles INVITROGEN DYNAL AS (NO) 2006-06-22 US disclosed
US-20060040113-A1 Cationically curable silicone compositions based on colloidal silica and anti-mist/anti-fouling hard coatings formed therefrom RHODIA CHIMIE (FR) 2006-02-23 US disclosed
EP-1573325-A1 PARTICLES Dynal Biotech ASA (NO) 2005-09-14 EP disclosed
US-20050029492-A1 Processing of semiconductor substrates with dense fluids comprising acetylenic diols and/or alcohols VERSUM MATERIALS US, LLC 2005-02-10 US disclosed
US-20050029490-A1 Processing of substrates with dense fluids comprising acetylenic diols and/or alcohols VERSUM MATERIALS US, LLC 2005-02-10 US disclosed
EP-1505146-A1 Processing of substrates with dense fluids comprising acetylenic diols and/or alcohols AIR PRODUCTS AND CHEMICALS, INC. (US) 2005-02-09 EP disclosed
WO-2004053490-A1 PARTICLES DYNAL BIOTECH ASA (NO) 2004-06-24 WO disclosed