SCHEMBL9513874

SCHEMBL9513874

FC(F)C(F)(F)C(F)(F)C(F)(F)C(F)OCC1CO1

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.35
TDP1 Q9NUW8 2/20 0.35
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 4/20 0.34
MAPK1 P28482 1/20 0.32
TP53 P04637 3/20 0.30
MAPT P10636 2/20 0.30
HPGD P15428 2/20 0.30
HIF1A Q16665 2/20 0.30
MEN1 O00255 1/20 0.30
CYP1A2 P05177 1/20 0.30
KMT2A Q03164 1/20 0.30
PPARG P37231 1/20 0.30
CYP3A4 P08684 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6243102 0.95 ALDH1A1 (0.33) TSHRTDP1KDM4EALDH1A1MAPK1
SCHEMBL10943101 0.89 ALDH1A1 (0.36) TSHRTDP1ALDH1A1MAPK1TP53
SCHEMBL1071671 0.87 ALDH1A1 (0.35) TSHRTDP1ALDH1A1MAPK1TP53
SCHEMBL6911632 0.84 ALDH1A1 (0.33) TSHRTDP1ALDH1A1MAPK1
SCHEMBL711179 0.83 ALDH1A1 (0.32) TSHRALDH1A1MAPK1
SCHEMBL711058 0.81 ALDH1A1 (0.32) TSHRALDH1A1MAPK1
SCHEMBL5077997 0.80 ALDH1A1 (0.31) ALDH1A1
SCHEMBL10938819 0.79 ALDH1A1 (0.38) TSHRTDP1ALDH1A1MAPK1TP53
SCHEMBL6396180 0.79 ALDH1A1 (0.30) ALDH1A1
SCHEMBL109265 0.79 ALDH1A1 (0.40) TSHRTDP1ALDH1A1MAPK1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0287092-B1 Antistatic Polymer Composition and Production thereof GOODRICH CO B F (US) 1993-11-03 EP disclosed
EP-0434011-A1 Additive for imparting electrostatic dissipative properties in plastic materials and method relating thereto THE B.F. GOODRICH COMPANY (US) 1991-06-26 EP disclosed
EP-0431634-A2 Vinyl halide polymer compositions having antistatic properties THE B.F. GOODRICH COMPANY (US) 1991-06-12 EP disclosed
US-5010139-A High molecular weight solids added to thermoplastic polymers used as molding materials; heat resistance; electrical apparatus THE B. F. GOODRICH COMPANY (US) 1991-04-23 US disclosed
EP-0287092-A2 Antistatic Polymer Composition and Production thereof THE B.F. GOODRICH COMPANY (US) 1988-10-19 EP disclosed