Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | GHSR | Q92847 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL10922249 | 0.94 | HPGD (0.43) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| Fumaric Acid SCHEMBL10922244 | 0.94 | HPGD (0.43) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL10923641 | 0.87 | KDM4E (0.61) | KMT2AKDM4EALDH1A1LMNAMTNR1A | |
| SCHEMBL11007885 | 0.86 | KDM4E (0.52) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10919901 | 0.86 | KDM4E (0.54) | KDM4EALDH1A1SMN1; SMN2MGLLGHSR | |
| SCHEMBL10923693 | 0.86 | LTA4H (0.51) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL10917658 | 0.83 | KDM4E (0.60) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| Oxalic Acid SCHEMBL10995840 | 0.83 | KDM4E (0.58) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10923638 | 0.82 | KDM4E (0.59) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL10920900 | 0.82 | HPGD (0.44) | MEN1KMT2AKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0066987-B1 | N-(ARYLOXYALKYL)-N'-(AMINO-ALKYL) UREAS | A.H. ROBINS COMPANY, INCORPORATED (US) | 1986-08-27 | — | — | EP | claimed |
| US-4500529-A | ANTIARRHYTHMIA AGENT | A. H. ROBINS COMPANY, INCORPORATED (US) | 1985-02-19 | — | — | US | claimed |