Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.47 |
| ▸ | MAPT | P10636 | 10/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 6/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10928328 | 1.00 | ALDH1A1 (0.47) | ALDH1A1MAPTSMN1; SMN2LMNAHPGD | |
| SCHEMBL2925357 | 0.85 | ALDH1A1 (0.53) | ALDH1A1MAPTSMN1; SMN2LMNAHPGD | |
| SCHEMBL27732122 | 0.81 | POLB (0.58) | ALDH1A1MAPTSMN1; SMN2LMNAHPGD | |
| SCHEMBL182652 | 0.80 | MAPT (0.52) | ALDH1A1MAPTSMN1; SMN2LMNAHPGD | |
| SCHEMBL7447406 | 0.79 | MAPK1 (0.54) | ALDH1A1MAPTSMN1; SMN2LMNAHPGD | |
| SCHEMBL6960 | 0.79 | ALDH1A1 (0.56) | ALDH1A1MAPTSMN1; SMN2LMNAHPGD | |
| SCHEMBL4261703 | 0.79 | MAPT (0.51) | ALDH1A1MAPTSMN1; SMN2LMNAHPGD | |
| SCHEMBL10920881 | 0.79 | ALDH1A1 (0.57) | ALDH1A1MAPTSMN1; SMN2LMNAHPGD | |
| SCHEMBL6813898 | 0.79 | CYP4F2 (0.48) | ALDH1A1MAPTSMN1; SMN2LMNAHPGD | |
| SCHEMBL182622 | 0.78 | RAB9A (0.56) | ALDH1A1MAPTSMN1; SMN2LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171702-A1 | Benzoxazinone derivatives, preparation and use | BEECHAM GROUP PLC (GB) | 1986-02-19 | — | — | EP | disclosed |