Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10928967 | 0.90 | POLB (0.43) | CYP19A1POLBIDO1SIGMAR1FNTA | |
| SCHEMBL10925022 | 0.89 | HMOX1 (0.43) | CYP19A1POLBCYP11B1CYP11B2TBXAS1 | |
| SCHEMBL10927338 | 0.88 | CYP17A1 (0.47) | CYP19A1POLBIDO1CYP11B1CYP11B2 | |
| SCHEMBL10927387 | 0.87 | CYP19A1 (0.49) | CYP19A1POLBIDO1FNTAFNTB | |
| SCHEMBL10929266 | 0.86 | CYP3A4 (0.40) | CYP11B1TBXAS1CYP2D6 | |
| SCHEMBL10929918 | 0.86 | POLB (0.46) | CYP19A1POLBIDO1TBXAS1 | |
| SCHEMBL10926068 | 0.85 | CYP19A1 (0.44) | CYP19A1CYP11B1CYP11B2TBXAS1 | |
| SCHEMBL10925660 | 0.85 | CYP19A1 (0.41) | CYP19A1IDO1CYP11B1CYP11B2TBXAS1 | |
| SCHEMBL10928025 | 0.85 | TBXAS1 (0.51) | TBXAS1 | |
| SCHEMBL10929490 | 0.85 | CYP19A1 (0.51) | CYP19A1POLBIDO1FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4518607-A | FUNGICIDES, BACXTERICIDES AND ANTIPROTOZOA AGENTS | SYNTEX (U.S.A.) INC. (US) | 1985-05-21 | — | — | US | disclosed |