SCHEMBL10928634

SCHEMBL10928634

CCCCCCCCN(CCCCCCCC)C(=O)C(CCCCCC)P(=O)(O)OCC(O)O

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PLA2G4A P47712 2/20 0.39
SMPD1 P17405 3/20 0.39
SGPL1 O95470 4/20 0.39
FDPS P14324 3/20 0.38
PLA2G2A P14555 1/20 0.38
LPAR5 Q9H1C0 2/20 0.37
LPAR6 P43657 1/20 0.37
LPAR1 Q92633 1/20 0.37
LPAR4 Q99677 1/20 0.37
LPAR2 Q9HBW0 1/20 0.37
LPAR3 Q9UBY5 1/20 0.37
ENPP2 Q13822 1/20 0.37
MMP1 P03956 1/20 0.37
MMP2 P08253 1/20 0.37
MMP3 P08254 1/20 0.37
MMP8 P22894 1/20 0.37
LAP3 P28838 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16697100 0.88 LPAR3 (0.42) SMPD1FDPSPLA2G2ALPAR1LPAR2
SCHEMBL16697211 0.82 FDPS (0.52) SMPD1FDPSMMP1MMP2MMP3
SCHEMBL10928628 0.80 FDPS (0.40) SMPD1FDPSMMP1MMP2MMP3
SCHEMBL11799989 0.79 FDPS (0.52) SMPD1FDPSLPAR2LPAR3MMP1
SCHEMBL16697061 0.78 LPAR3 (0.40) SMPD1FDPSLPAR1LPAR2LPAR3
SCHEMBL13596676 0.70 S1PR1 (0.58) LPAR5LPAR6LPAR1LPAR4LPAR2
Ethylene SCHEMBL29186282 0.70 GPR84 (0.55)
SCHEMBL13924966 0.69 SMPD1 (0.46) SMPD1FDPSLPAR1LPAR2LPAR3
SCHEMBL16221457 0.68 CA1 (0.52) FDPS
SCHEMBL22631845 0.67 GPR84 (0.52)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4525289-A NON-CORROSIVE, FRICTION AND WEAR RESISTANT THE PROCTER & GAMBLE COMPANY (US) 1985-06-25 US disclosed
EP-0083124-A1 Alpha phosphonoamides, and lubricant and hydrocarbon fuel compositions containing them THE PROCTER & GAMBLE COMPANY (US) 1983-07-06 EP disclosed