Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 6/20 | 0.40 |
| ▸ | TOP2A | P11388 | 3/20 | 0.40 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10654948 | 0.89 | ADRB2 (0.46) | ADRB2KDM4EHSD17B10ABCC4LMNA | |
| SCHEMBL5809336 | 0.81 | ADRB2 (0.53) | ADRB2KDM4EHSD17B10ABCC4LMNA | |
| SCHEMBL10651097 | 0.81 | ADRB2 (0.46) | ADRB2KDM4EHSD17B10ABCC4LMNA | |
| SCHEMBL5422476 | 0.80 | ADRB2 (0.51) | ADRB2KDM4EHSD17B10ABCC4LMNA | |
| SCHEMBL10412649 | 0.77 | ADRB2 (0.49) | ADRB2KDM4EHSD17B10ABCC4LMNA | |
| SCHEMBL10472546 | 0.77 | ADRB2 (0.49) | ADRB2KDM4EHSD17B10ABCC4LMNA | |
| SCHEMBL8942057 | 0.77 | ADRB2 (0.49) | ADRB2KDM4EHSD17B10ABCC4LMNA | |
| SCHEMBL9757281 | 0.77 | DPP4 (0.51) | ADRB2KDM4EHSD17B10ABCC4LMNA | |
| SCHEMBL7005348 | 0.76 | HPGD (0.41) | ADRB2KDM4EHSD17B10ABCC4LMNA | |
| SCHEMBL7230077 | 0.76 | ADRB2 (0.50) | ADRB2KDM4EHSD17B10ABCC4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60032790-A | — | — | None | — | — | JP | disclosed |
| JP-60028978-A | — | — | None | — | — | JP | disclosed |
| JP-S6032790-A | 1,8-NAPHTHYRIDINES | DAINIPPON PHARMACEUT CO LTD | 1985-02-19 | — | — | JP | disclosed |
| JP-S6028978-A | 1,8-NAPHTHYRIDINE DERIVATIVE | DAINIPPON PHARMACEUT CO LTD | 1985-02-14 | — | — | JP | disclosed |