Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | TEK | Q02763 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6475552 | 0.92 | HRH1 (0.45) | TDP1TACR1OPRD1HRH1SLC6A4 | |
| SCHEMBL6482143 | 0.83 | HRH1 (0.54) | TDP1TACR1OPRD1HRH1SLC6A4 | |
| SCHEMBL9844393 | 0.83 | OPRD1 (0.42) | TDP1OPRD1SLC6A4SIGMAR1 | |
| Hydrochloric Acid SCHEMBL5957369 | 0.82 | HRH1 (0.55) | TDP1TACR1OPRD1HRH1SLC6A4 | |
| Hydrochloric Acid SCHEMBL27546451 | 0.78 | HRH1 (0.38) | TDP1MAPTHRH1SLC6A4SLC6A2 | |
| SCHEMBL27980649 | 0.71 | OPRD1 (0.44) | OPRD1SLC6A4SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8693217 | 0.71 | TDP1 (0.43) | TDP1ALDH1A1LMNAMAPTSLC6A4 | |
| SCHEMBL16757280 | 0.71 | TDP1 (0.46) | TDP1ALDH1A1KDM4ETACR1OPRD1 | |
| SCHEMBL5683230 | 0.71 | TDP1 (0.41) | TDP1TACR1OPRD1HRH1SLC6A4 | |
| SCHEMBL7337323 | 0.70 | TDP1 (0.42) | TDP1OPRD1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4525358-A | ANTIHISTAMINES, ANTIALLERGENS, ANTISPASMODICS, BRONCHODILATORS | UCB PHARMACEUTICALS, INC. (US) | 1985-06-25 | — | — | US | disclosed |