Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL345936 | 0.86 | HCAR2 (0.56) | LMNAMAPK1HTTHCAR2MGAM | |
| SCHEMBL11792235 | 0.86 | HCAR2 (0.56) | LMNAMAPK1HTTHCAR2MGAM | |
| SCHEMBL345935 | 0.86 | HCAR2 (0.56) | LMNAMAPK1HTTHCAR2MGAM | |
| SCHEMBL28251620 | 0.86 | HCAR2 (0.56) | LMNAMAPK1HTTHCAR2MGAM | |
| SCHEMBL10388246 | 0.85 | LMNA (0.48) | LMNAMAPK1HTTHCAR2ATM | |
| SCHEMBL330246 | 0.84 | HCAR2 (0.54) | LMNAMAPK1HTTHCAR2MGAM | |
| SCHEMBL8654856 | 0.84 | HCAR2 (0.54) | LMNAMAPK1HTTHCAR2MGAM | |
| SCHEMBL38662185 | 0.84 | HCAR2 (0.54) | LMNAMAPK1HTTHCAR2MGAM | |
| SCHEMBL7020452 | 0.84 | HCAR2 (0.54) | LMNAMAPK1HTTHCAR2MGAM | |
| SCHEMBL329729 | 0.84 | HCAR2 (0.54) | LMNAMAPK1HTTHCAR2MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4517308-A | ABSORBERS, BINDING, SHAPING | COLLO GMBH (DE) | 1985-05-14 | — | — | US | disclosed |