Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 14/20 | 0.80 |
| ▸ | ADRB2 | P07550 | 11/20 | 0.80 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.80 |
| ▸ | SLC2A1 | P11166 | 4/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.61 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7153660 | 0.89 | ADRB3 (1.00) | ADRB3ADRB2ADRB1SLC2A1CYP2D6 | |
| SCHEMBL7153657 | 0.89 | ADRB3 (1.00) | ADRB3ADRB2ADRB1SLC2A1CYP2D6 | |
| SCHEMBL10934792 | 0.89 | ADRB3 (1.00) | ADRB3ADRB2ADRB1SLC2A1CYP2D6 | |
| SCHEMBL9417734 | 0.88 | ADRB3 (0.98) | ADRB3ADRB2ADRB1SLC2A1CYP2D6 | |
| SCHEMBL11168722 | 0.85 | SLC2A1 (0.72) | ADRB3ADRB2ADRB1SLC2A1CYP2D6 | |
| SCHEMBL8402065 | 0.85 | ADRB3 (0.70) | ADRB3ADRB2ADRB1SLC2A1CYP2D6 | |
| SCHEMBL10840645 | 0.84 | SLC2A1 (0.70) | ADRB3ADRB2ADRB1SLC2A1CYP2D6 | |
| SCHEMBL10890383 | 0.84 | SLC2A1 (0.70) | ADRB3ADRB2ADRB1SLC2A1CYP2D6 | |
| SCHEMBL8402465 | 0.84 | ADRB3 (0.69) | ADRB3ADRB2ADRB1SLC2A1CYP2D6 | |
| SCHEMBL10772841 | 0.84 | SLC2A1 (0.92) | ADRB3ADRB2ADRB1SLC2A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0052963-B1 | SECONDARY AMINES | BEECHAM GROUP PLC (GB) | 1985-02-20 | — | — | EP | claimed |
| US-4382958-A | Secondary amines and compositions for treatment of hypoglycaemia or obesity | BEECHAM GROUP LIMITED (GB) | 1983-05-10 | — | — | US | claimed |
| EP-0052963-A1 | Secondary amines | BEECHAM GROUP PLC (GB) | 1982-06-02 | — | — | EP | claimed |
| EP-0052963-B1 | SECONDARY AMINES | BEECHAM GROUP PLC (GB) | 1985-02-20 | — | — | EP | disclosed |
| US-4382958-A | Secondary amines and compositions for treatment of hypoglycaemia or obesity | BEECHAM GROUP LIMITED (GB) | 1983-05-10 | — | — | US | disclosed |
| EP-0052963-A1 | Secondary amines | BEECHAM GROUP PLC (GB) | 1982-06-02 | — | — | EP | disclosed |